Ligase Market Size, Share, Price, Growth, Trends, Report 2027

Report Description

The global ligase market is anticipated to observe impressive growth during the forecast period, 2023-2027. The major factors include rising prevalence of infectious, genetic, and chronic diseases, and increase in R&D activities are impelling the growth of the market. Ligases are enzymes that catalyzes the reaction by joining two molecules by forming a new chemical bond. Ligase has a crucial role in the molecular diagnostics method, as it makes sure the safety and effective application of targeted therapeutics. The other factors supporting the market’s growth are, increasing demand for disease treatment, increasing investments in the R&D, growing research & development, expansion of diagnostics and pharmaceutical companies, adoption of advanced technology, and rising world population. Also, the increasing strategic growth such as mergers, collaborations, and acquisitions are strengthening the growth of the market. For instance, in 2021, BLIRT S.A. enlarged its laboratory facility at Technology Park and Gdansk Science. The new laboratory is involved in growing its production scale for key enzymes and improving production processes.

Growing Need for Ligases in Disease Treatment

The surge in incidences of chronic diseases, infectious diseases, and genetic disorders, across the globe are bolstering the growth of the market. Rising number of patients suffering from one of these diseases is a contributing factor. Thus, the need for better treatment to provide better patient care is fueling the growth of the market. Not only geriatric population but younger generation are prone to these diseases due to unhealthy choices, lifestyle changes, consumption of fast foods and other. Thus, strengthening the growth of the market. For instance, according to WHO, every year 17.9 million people die from cardiovascular diseases, followed by 9.3 million deaths by cancer, 4.1 million deaths from chronic respiratory diseases, and lastly 2.0 million deaths caused by diabetes including kidney disease. Similarly, according to the estimation of WHO, 10 out of every 1000 people are affected by genetic diseases.

Increasing R&D and Heavy Investments Fuels the Market Growth

Rise in research and development (R&D) activities across the globe to use ligase as a therapeutic intervention is propelling the growth of the market. Owing to the increase in research activities, they are used for various purposes such as mutation detection, cloning, drug targets, and others, thus, in turn, impelling the growth of the market. For instance, in March 2022, a research study named "The Role of SUMO E3 Ligases in Signaling Pathway of Cancer Cells" stated that small ubiquitin-like modifier (SUMO)ylation is a reversible post-translational modification that plays a vital role in several aspects of cell physiology, including cell cycle regulation, protein trafficking, and DNA damage repair, which are essential for cell homeostasis. Moreover, the rising investments in the R&D activities for enzyme-based molecular diagnostics is facilitating the growth of the market. In 2021, Merck invested $282.5 million at its global headquarters in Darmstadt. Company is focusing in building a new translational science center for its healthcare business sector and for a new learning center.

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Market Segmentation

The global ligase market is segmented into product, source, application, end user and company. Based on product, the market is segmented into quick ligase, T4 DNA ligase, E.Coli DNA ligase, T4 RNA ligase, and others. Based on source, the market is segmented into archaebacterium, escherichia coli, thermus thermophilus, and others. Based on application, the market is segmented into ligase chain reaction, ligase detection reaction, next generation sequencing, molecular cloning, and others. Based on end user, the market is divided into biotechnology & pharmaceutical companies, academic & research institutions, and others. In terms of country, the United States is expected to be a lucrative market in the forecast period due to rising number of research and development and clinical trials programs in the country.

Market Players

Bio-Rad Laboratories, Inc., Agilent Technologies, Inc., Codexis, Inc., F. Hoffmann-La Roche AG, Merck KGaA, Promega Corporation, QIAGEN N.V., ArcticZymes Technologies ASA, Thermo Fisher Scientific, Inc., and Takara Bio Inc. are some of the leading companies operating in the market.

Attribute	Details
Base Year	2021
Historic Data	2017 – 2020
Estimated Year	2022
Forecast Period	2023 – 2027
Quantitative Units	Revenue in USD Million, Volume Units and CAGR for 2017-2021 and 2022-2027
Report coverage	Revenue forecast, Volume forecast company share, competitive landscape, growth factors, and trends
Segments covered	· Product · Source · Application · End User · Company
Regional scope	North America; Asia Pacific; Europe & CIS; South America; Middle East & Africa
Country scope	United States; Canada; Mexico; China; India; Japan; South Korea; Germany; France; United Kingdom; Spain; Italy; Brazil; Argentina; Colombia; South Africa; UAE; Saudi Arabia; South Africa
Key companies profiled	Bio-Rad Laboratories, Inc., Agilent Technologies, Inc., Codexis, Inc., F. Hoffmann-La Roche AG, Merck KGaA, Promega Corporation, QIAGEN N.V., ArcticZymes Technologies ASA, Thermo Fisher Scientific, Inc., and Takara Bio Inc.
Customization scope	10% free report customization with purchase. Addition or alteration to country, regional & segment scope.
Pricing and purchase options	Avail customized purchase options to meet your exact research needs. Explore purchase options
Delivery Format	PDF and Excel through Email (We can also provide the editable version of the report in PPT/Word format on special request)

Report Scope:

In this report, global ligase market has been segmented into following categories, in addition to the industry trends which have also been detailed below:

· Ligase Market, By Product:

o Quick Ligase

o T4 DNA Ligase

o E.Coli DNA Ligase

o T4 RNA Ligase

o Others

· Ligase Market, By Source:

o Archaebacterium

o Escherichia coli

o Thermus thermophilus

o Others

· Ligase Market, By Application:

o Ligase Chain Reaction

o Ligase Detection Reaction

o Next Generation Sequencing

o Molecular Cloning

o Others

· Ligase Market, By End User:

Biotechnology & Pharmaceutical Companies
Academic & Research Institutions
Others

· Ligase Market, By Region:

North America

United States
Canada
Mexico

Asia-Pacific

China
India
Japan
Australia
South Korea

Europe & CIS

Germany
France
United Kingdom
Spain
Italy

South America

Brazil
Argentina
Colombia

Middle East & Africa

§ South Africa

§ Saudi Arabia

§ UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in Global Ligase Market

Available Customizations:

With the given market data, TechSci Research offers customizations according to a company’s specific needs. The following customization options are available for the report:

Company Information

Detailed analysis and profiling of additional market players (up to five).

Ligase Market is an upcoming report to be released soon. If you wish an early delivery of this report or want to confirm the date of release, please contact us at [email protected]

Table of content

1. Product Overview

2. Research Methodology

3. Executive Summary

4. Impact of COVID-19 on Global Ligase Market

5. Voice of Customer

6. Global Ligase Market Outlook

6.1. Market Size & Forecast

6.1.1. By Value

6.2. Market Share & Forecast

6.2.1. By Product (Quick Ligase, T4 DNA Ligase, E.Coli DNA Ligase, T4 RNA Ligase, Others)

6.2.2. By Source (Archaebacterium, Escherichia coli, Thermus thermophilus, Others)

6.2.3. By Application (Ligase Chain Reaction, Ligase Detection Reaction, Next Generation Sequencing, Molecular Cloning, Others)

6.2.4. By End User (Biotechnology & Pharmaceutical Companies, Academic & Research Institutions, Others)

6.2.5. By Region

6.2.6. By Company (2021)

6.3. Market Map

7. North America Ligase Market Outlook

7.1. Market Size & Forecast

7.1.1. By Value

7.2. Market Share & Forecast

7.2.1. By Product

7.2.2. By Source

7.2.3. By Application

7.2.4. By End User

7.2.5. By Country

7.3. North America: Country Analysis

7.3.1. United States Ligase Market Outlook

7.3.1.1. Market Size & Forecast

7.3.1.1.1. By Value

7.3.1.2. Market Share & Forecast

7.3.1.2.1. By Product

7.3.1.2.2. By Source

7.3.1.2.3. By Application

7.3.1.2.4. By End User

7.3.2. Mexico Ligase Market Outlook

7.3.2.1. Market Size & Forecast

7.3.2.1.1. By Value

7.3.2.2. Market Share & Forecast

7.3.2.2.1. By Product

7.3.2.2.2. By Source

7.3.2.2.3. By Application

7.3.2.2.4. By End User

7.3.3. Canada Ligase Market Outlook

7.3.3.1. Market Size & Forecast

7.3.3.1.1. By Value

7.3.3.2. Market Share & Forecast

7.3.3.2.1. By Product

7.3.3.2.2. By Source

7.3.3.2.3. By Application

7.3.3.2.4. By End User

8. Europe Ligase Market Outlook

8.1. Market Size & Forecast

8.1.1. By Value

8.2. Market Share & Forecast

8.2.1. By Product

8.2.2. By Source

8.2.3. By Application

8.2.4. By End User

8.2.5. By Country

8.3. Europe: Country Analysis

8.3.1. France Ligase Market Outlook

8.3.1.1. Market Size & Forecast

8.3.1.1.1. By Value

8.3.1.2. Market Share & Forecast

8.3.1.2.1. By Product

8.3.1.2.2. By Source

8.3.1.2.3. By Application

8.3.1.2.4. By End User

8.3.2. Germany Ligase Market Outlook

8.3.2.1. Market Size & Forecast

8.3.2.1.1. By Value

8.3.2.2. Market Share & Forecast

8.3.2.2.1. By Product

8.3.2.2.2. By Source

8.3.2.2.3. By Application

8.3.2.2.4. By End User

8.3.3. United Kingdom Ligase Market Outlook

8.3.3.1. Market Size & Forecast

8.3.3.1.1. By Value

8.3.3.2. Market Share & Forecast

8.3.3.2.1. By Product

8.3.3.2.2. By Source

8.3.3.2.3. By Application

8.3.3.2.4. By End User

8.3.4. Italy Ligase Market Outlook

8.3.4.1. Market Size & Forecast

8.3.4.1.1. By Value

8.3.4.2. Market Share & Forecast

8.3.4.2.1. By Product

8.3.4.2.2. By Source

8.3.4.2.3. By Application

8.3.4.2.4. By End User

8.3.5. Spain Ligase Market Outlook

8.3.5.1. Market Size & Forecast

8.3.5.1.1. By Value

8.3.5.2. Market Share & Forecast

8.3.5.2.1. By Product

8.3.5.2.2. By Source

8.3.5.2.3. By Application

8.3.5.2.4. By End User

9. Asia-Pacific Ligase Market Outlook

9.1. Market Size & Forecast

9.1.1. By Value

9.2. Market Share & Forecast

9.2.1. By Product

9.2.2. By Source

9.2.3. By Application

9.2.4. By End User

9.2.5. By Country

9.3. Asia-Pacific: Country Analysis

9.3.1. China Ligase Market Outlook

9.3.1.1. Market Size & Forecast

9.3.1.1.1. By Value

9.3.1.2. Market Share & Forecast

9.3.1.2.1. By Product

9.3.1.2.2. By Source

9.3.1.2.3. By Application

9.3.1.2.4. By End User

9.3.2. India Ligase Market Outlook

9.3.2.1. Market Size & Forecast

9.3.2.1.1. By Value

9.3.2.2. Market Share & Forecast

9.3.2.2.1. By Product

9.3.2.2.2. By Source

9.3.2.2.3. By Application

9.3.2.2.4. By End User

9.3.3. Japan Ligase Market Outlook

9.3.3.1. Market Size & Forecast

9.3.3.1.1. By Value

9.3.3.2. Market Share & Forecast

9.3.3.2.1. By Product

9.3.3.2.2. By Source

9.3.3.2.3. By Application

9.3.3.2.4. By End User

9.3.4. South Korea Ligase Market Outlook

9.3.4.1. Market Size & Forecast

9.3.4.1.1. By Value

9.3.4.2. Market Share & Forecast

9.3.4.2.1. By Product

9.3.4.2.2. By Source

9.3.4.2.3. By Application

9.3.4.2.4. By End User

9.3.5. Australia Ligase Market Outlook

9.3.5.1. Market Size & Forecast

9.3.5.1.1. By Value

9.3.5.2. Market Share & Forecast

9.3.5.2.1. By Product

9.3.5.2.2. By Source

9.3.5.2.3. By Application

9.3.5.2.4. By End User

10. South America Ligase Market Outlook

10.1. Market Size & Forecast

10.1.1. By Value

10.2. Market Share & Forecast

10.2.1. By Product

10.2.2. By Source

10.2.3. By Application

10.2.4. By End User

10.2.5. By Country

10.3. South America: Country Analysis

10.3.1. Brazil Ligase Market Outlook

10.3.1.1. Market Size & Forecast

10.3.1.1.1. By Value

10.3.1.2. Market Share & Forecast

10.3.1.2.1. By Product

10.3.1.2.2. By Source

10.3.1.2.3. By Application

10.3.1.2.4. By End User

10.3.2. Argentina Ligase Market Outlook

10.3.2.1. Market Size & Forecast

10.3.2.1.1. By Value

10.3.2.2. Market Share & Forecast

10.3.2.2.1. By Product

10.3.2.2.2. By Source

10.3.2.2.3. By Application

10.3.2.2.4. By End User

10.3.3. Colombia Ligase Market Outlook

10.3.3.1. Market Size & Forecast

10.3.3.1.1. By Value

10.3.3.2. Market Share & Forecast

10.3.3.2.1. By Product

10.3.3.2.2. By Source

10.3.3.2.3. By Application

10.3.3.2.4. By End User

11. Middle East and Africa Ligase Market Outlook

11.1. Market Size & Forecast

11.1.1. By Value

11.2. Market Share & Forecast

11.2.1. By Product

11.2.2. By Source

11.2.3. By Application

11.2.4. By End User

11.2.5. By Country

11.3. MEA: Country Analysis

11.3.1. South Africa Ligase Market Outlook

11.3.1.1. Market Size & Forecast

11.3.1.1.1. By Value

11.3.1.2. Market Share & Forecast

11.3.1.2.1. By Product

11.3.1.2.2. By Source

11.3.1.2.3. By Application

11.3.1.2.4. By End User

11.3.2. Saudi Arabia Ligase Market Outlook

11.3.2.1. Market Size & Forecast

11.3.2.1.1. By Value

11.3.2.2. Market Share & Forecast

11.3.2.2.1. By Product

11.3.2.2.2. By Source

11.3.2.2.3. By Application

11.3.2.2.4. By End User

11.3.3. UAE Ligase Market Outlook

11.3.3.1. Market Size & Forecast

11.3.3.1.1. By Value

11.3.3.2. Market Share & Forecast

11.3.3.2.1. By Product

11.3.3.2.2. By Source

11.3.3.2.3. By Application

11.3.3.2.4. By End User

12. Market Dynamics

12.1. Drivers

12.2. Challenges

13. Market Trends & Developments

14. Competitive Landscape

14.1. Bio-Rad Laboratories, Inc.

14.2. Agilent Technologies, Inc.

14.3. Codexis, Inc.

14.4. F. Hoffmann-La Roche AG

14.5. Merck KGaA

14.6. Promega Corporation

14.7. QIAGEN N.V.

14.8. ArcticZymes Technologies ASA

14.9. Thermo Fisher Scientific, Inc.

14.10. Takara Bio Inc.

15. Strategic Recommendations

Figures and Tables

Frequently asked questions

What are the major drivers for the Global Ligase Market?

Growing prevalence of infectious, genetic, and chronic diseases, rising demand of ligase as disease treatment, and extensive research and development are driving the demand for the global ligase market.

Who are the top players operating in the Global Ligase Market?

Bio-Rad Laboratories, Inc., Agilent Technologies, Inc., Codexis, Inc., F. Hoffmann-La Roche AG, Merck KGaA, Promega Corporation, QIAGEN N.V., ArcticZymes Technologies ASA, Thermo Fisher Scientific, Inc., and Takara Bio Inc. are the key players operating in the global ligase market.

What are the key factors hampering growth for the Global Ligase Market?

They have minimal activity on short cohesive and blunt substrates in end-joining reactions, and certain NAD-dependent thermostable DNA ligase, which is used in vitro, can ligate only an inadequate number of nicks may hamper the growth of the global ligase market.