Press Release

Ligase Market to be dominated by Rising Prevalence of Infectious, Genetic, and Chronic Diseases through 2027

Growing R&D activities and growing need for disease treatment to drive the ligase market in the forecast period, 2023-2027.

According to TechSci Research report, “Ligase
Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2017-2027, the global ligase market is anticipated to grow at a significant rate in the forecast period, 2023-2027. The rising incidence of infectious, genetic, and chronic diseases, and extensive research and development are the primary factors driving the demand for the global ligase market. Growing adoption of advanced technology, expansion of diagnostics and pharmaceutical companies, rise in world population, growing research & development, expansion of biopharmaceutical industries and biopharma production, growing need of ligase in disease treatment and heavy investments in healthcare sector are expected to influence the market demand. Also, increasing strategic growth is also a key factor for increasing the growth of the ligase market, globally.

However, the have minimal activity on short cohesive and blunt substrates in end-joining reactions, and certain NAD-dependent thermostable DNA ligase, which is used in vitro, can ligate only inadequate number of nicks may hamper the growth of the global ligase market.

Browse over XX market data Figures spread through 110 Pages and an in-depth TOC on "Ligase Market"

The global ligase market is segmented into product, source, application, end user and company.

Based on product, the market is segmented into quick ligase, T4 DNA ligase, E.Coli DNA ligase, T4 RNA ligase, and others. The T4 DNA ligase segment is expected to hold the largest market share. This is attributed to the most used ligase type among suppliers providing kits and enzymes to their end users.

Based on source, the market is segmented into archaebacterium, Escherichia coli, thermus thermophilus, and others. The Escherichia coli segment is anticipated to grow during the forecast period. This is attributed to widely used to unite the recombinant ends of molecules prior to their launch into the cell.

Based on application, the market is segmented into ligase chain reaction, ligase detection reaction, next generation sequencing, molecular cloning, and others. The molecular cloning segment is anticipated to grow during the forecast period. This is attributed to wide applications, including the cloning of stem cells, which aid in offering treatment for various diseases.

Based on end user, the market is divided into biotechnology & pharmaceutical companies, academic & research institutions, and others. The academic & research institutions segment is anticipated to grow during the forecast period. This is attributed to rising research on the diagnostic application of ligase enzyme.

Major companies operating in global ligase market are:

  • Bio-Rad Laboratories, Inc.
  • Agilent Technologies, Inc.
  • Codexis, Inc.
  • F. Hoffmann-La Roche AG
  • Merck KGaA
  • Promega Corporation
  • QIAGEN N.V.
  • ArcticZymes Technologies ASA
  • Thermo Fisher Scientific, Inc.
  • Takara Bio Inc.


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“North America region dominates the market in 2021 and is expected to maintain its dominance in the coming years due to the high occurrence of genetic defects and a rise in the number of individuals needing long-term care in the region. Increase in investments for R&D to promote the production of ligases as therapeutics for various, presence of many leading players, the well-established end-user industries, and extensive advancements in technology, in the region is another key factor.  Also, the high number of firms with a strategic pipeline in the region are expected to propel the global ligase market growth till 2027” said Mr. Karan Chechi, Research Director with TechSci Research, a research based global management consulting firm.

Ligase Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2017-2027 Segmented By Product (Quick Ligase, T4 DNA Ligase, E.Coli DNA Ligase, T4 RNA Ligase, Others), By Source (Archaebacterium, Escherichia coli, Thermus thermophilus, Others), By Application (Ligase Chain Reaction, Ligase Detection Reaction, Next Generation Sequencing, Molecular Cloning, Others), By End User (Biotechnology & Pharmaceutical Companies, Academic & Research Institutions, Others), By company and By Region”, has evaluated the future growth potential of global ligase market and provides statistics & information on market size, structure, and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in global ligase market.


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