|
Forecast
Period
|
2026-2030
|
|
Market
Size (2024)
|
USD
2.01 Million
|
|
Market
Size (2030)
|
USD
2.58 Million
|
|
CAGR
(2025-2030)
|
4.23%
|
|
Fastest
Growing Segment
|
Antimalarial
Tablets
|
|
Largest
Market
|
Southern
Vietnam
|
Market Overview
Vietnam Artemisinic
Acid Market was valued at USD 2.01 Million in 2024
and is expected to reach USD 2.58 Million by 2030 with a CAGR of 4.23% during
the forecast period. The
growth of the Vietnam Artemisinic Acid Market is primarily driven by the
increasing demand for artemisinin-based combination therapies (ACTs) in the
fight against malaria. As the prevalence of malaria remains a significant
health issue in Vietnam, the need for effective treatments is high. Artemisinic
acid, a key precursor in the synthesis of artemisinin, plays a crucial role in
producing ACTs, making it vital for the pharmaceutical industry. The focus on
cost-effective and sustainable production of artemisinin, as well as ongoing
research into the use of artemisinic acid for other medical applications, such
as cancer treatments, further drives market growth. Government initiatives to
combat malaria and support the local pharmaceutical industry also contribute to
the increasing demand for artemisinic acid in Vietnam.
Key Market Drivers
Rising Prevalence of Malaria
The
increasing prevalence of malaria in Vietnam is one of the most significant
drivers of the Artemisinic Acid Market. Despite considerable efforts to combat
the disease, malaria remains endemic in many parts of the country, particularly
in rural and remote regions. According to the World Health Organization (WHO),
malaria continues to be a major health concern in Southeast Asia, including
Vietnam. In 2022, Vietnam reported 412 cases of malaria, including vivax,
falciparum, and mixed types. P. vivax accounted for approximately 40% of these
cases (163 out of 412). The malaria situation in Vietnam is complex, with
variations in incidence across different regions and among various populations.
The government has launched extensive programs to combat malaria through
preventive measures, such as mosquito nets and insecticides, alongside
treatments like artemisinin-based therapies. As the demand for ACTs rises in
response to the need for effective malaria treatments, the demand for
artemisinic acid, the precursor to artemisinin, also increases, thereby driving
market growth. The Vietnamese pharmaceutical industry is heavily invested in
the development of affordable and sustainable solutions for the malaria
epidemic, further enhancing the demand for artemisinic acid.
Support from Government and
International Health Organizations
The
government of Vietnam, in collaboration with international health organizations
such as the World Health Organization (WHO) and the Global Fund to Fight AIDS,
Tuberculosis, and Malaria, plays a crucial role in driving the demand for Artemisinic
acid. The Government of Vietnam is committed to eliminating malaria by 2030.
NIMPE is actively collaborating with regional IMPEs, provincial health
departments, and global health partners to achieve this objective. These
organizations have contributed to various public health campaigns aimed at
eradicating malaria. In addition to funding and resources for treatment
programs, the Vietnamese government has been promoting the local production of
ACTs to reduce dependence on imported medicines. By encouraging domestic
production and setting up favorable policies for the pharmaceutical industry,
the government has ensured a steady demand for artemisinic acid. As these
initiatives continue to gain momentum, the market for artemisinic acid in
Vietnam will see further expansion.
Cost-Effectiveness of
Artemisinic Acid Production
The
relatively lower cost of producing Artemisinic acid compared to its derived
compound, artemisinin, plays a crucial role in driving the growth of the
Vietnam Artemisinic Acid Market. Artemisinic acid is a key precursor in the
production of artemisinin, a critical active ingredient used in artemisinin-based
combination therapies (ACTs), which are the first-line treatment for malaria.
The traditional method of producing artemisinin, which involves extracting it
from the leaves of the Artemisia annua plant, is often associated with high
costs due to the labor-intensive cultivation process, dependence on
environmental factors, and fluctuations in agricultural yields. In contrast,
artemisinic acid can be synthesized more efficiently and cost-effectively through
various biotechnological processes, such as microbial fermentation and
synthetic biology.
One
of the most significant advantages of producing artemisinic acid is its ability
to be synthesized in the laboratory using biotechnological methods, which are
not only cost-effective but also sustainable. This shift towards
biotechnological production has made it easier for manufacturers to generate
large quantities of artemisinic acid at a lower price point, reducing reliance
on plant-based sources and mitigating the risks associated with agricultural
variability. Microbial fermentation, which is a widely adopted method in the
production of artemisinic acid, involves the use of genetically engineered
microorganisms, such as yeast or bacteria, to convert simple sugars into
artemisinic acid. This process is scalable, environmentally friendly, and
significantly more efficient than traditional methods. Advancements in
synthetic biology have further improved the production efficiency of
artemisinic acid, allowing for even greater yields with fewer resources.
Increasing Demand for Malaria
Treatments in Southeast Asia
The
demand for effective malaria treatments, including artemisinin-based
combination therapies, is not only limited to Vietnam but is also increasing
across Southeast Asia. Vietnam serves as a critical market in this region,
where malaria continues to present a public health challenge. In a study
titled, “Risk factors for malaria in high incidence areas of Viet Nam: a
case–control study”,
a survey was conducted with 1,000 malaria-positive cases and 1,000
malaria-negative controls, matched by age and gender. The participants
self-presented at commune health stations (CHS) in Binh Phuoc, Dak Nong, and
Dak Lak Provinces. Malaria diagnoses were confirmed using microscopy, rapid
diagnostic tests, and PCR. Participants were interviewed about 50 potential
malaria risk factors, including occupation, forest visits, travel history,
healthcare-seeking behavior, and previous use of anti-malaria interventions.
Trained government health workers enrolled the participants, and the samples
were analyzed in government laboratories in Vietnam.
The
rising resistance to traditional malaria treatments in certain parts of
Southeast Asia has made artemisinin-based therapies even more important. As the
region's demand for ACTs grows, the need for artemisinic acid, the key raw
material in the production of these therapies, is set to increase. The growing
regional demand for these life-saving treatments will contribute significantly
to the expansion of the artemisinic acid market in Vietnam.
Growing Focus on
Sustainability and Self-Sufficiency
There
is a growing emphasis on sustainability and self-sufficiency in Vietnam’s
healthcare sector, which has become a critical part of the country’s broader
economic and social development strategies. Over the past few years, the
Vietnamese government has made concerted efforts to address the nation’s
dependency on foreign pharmaceutical imports, which are often costly and
subject to global supply chain disruptions. This increased focus on local
pharmaceutical production is seen as a vital step in strengthening the
country’s healthcare system, reducing reliance on external markets, and
ensuring that essential medicines remain accessible and affordable for all
citizens, particularly those in rural and underserved areas.
One
of the key components of this drive towards self-sufficiency is the local
production of artemisinin and other active pharmaceutical ingredients (APIs),
such as artemisinic acid. Artemisinin-based combination therapies (ACTs) are
considered the gold standard in malaria treatment, and their widespread
availability is crucial for public health, particularly in malaria-endemic
regions like Vietnam. Historically, Vietnam has relied on the import of
artemisinin and related compounds for the production of ACTs, which has led to
vulnerability in the supply chain. The price fluctuations of these imported
ingredients have made it difficult for the Vietnamese government to guarantee
affordable treatments for its population, especially in the face of rising
demand for antimalarial drugs.
Expanding Role of Artemisinic
Acid in Other Medical Applications
In
recent years, researchers have explored the potential of artemisinic acid in
other medical applications beyond malaria treatment, such as cancer therapies
and antimicrobial treatments. This expanding research into the broader
therapeutic uses of artemisinic acid is expected to drive demand in the coming
years. As new applications for artemisinic acid are discovered, the market for
the compound will likely experience growth, as the pharmaceutical industry
diversifies its use of this vital precursor. If clinical studies confirm the
efficacy of artemisinic acid in treating other diseases, it will open new
markets and increase the global demand for artemisinic acid, including in
Vietnam.
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Key Market Challenges
Regulatory and Quality Control
Issues
The
Vietnam Artemisinic Acid Market also faces significant challenges related to
regulatory frameworks and quality control. As the market grows and artemisinic
acid production ramps up, ensuring consistent product quality becomes
increasingly difficult. This challenge is compounded by the complexity of the
regulatory environment surrounding the production, sale, and distribution of
pharmaceutical ingredients like artemisinic acid. Regulatory requirements for
the approval of artemisinin-based combination therapies (ACTs) and other
pharmaceuticals containing artemisinic acid can vary widely, both within
Vietnam and in international markets. Navigating these regulatory requirements
often involves long approval timelines, stringent testing protocols, and high compliance
costs for manufacturers.
Ensuring
that artemisinic acid meets the required pharmaceutical-grade quality is
essential, particularly since it is a crucial component in the formulation of
ACTs used in the treatment of malaria. Any inconsistencies or deviations in the
quality of artemisinic acid can compromise the efficacy of the final drug
product, leading to suboptimal treatment outcomes for patients. This is
particularly concerning in regions like Vietnam, where access to high-quality
malaria treatments can significantly affect public health. Inadequate quality
control mechanisms can also lead to wasted resources and damage the reputation
of local producers in the global market.
The
lack of a standardized framework for quality assurance in the production of
artemisinic acid is a challenge that has hindered the full potential of the
market. Small-scale producers or those operating without internationally
recognized certifications may struggle to meet the standards required for
domestic and international trade. This makes it difficult for them to gain a
competitive edge in the market, particularly when competing with international
manufacturers that adhere to strict Good Manufacturing Practice (GMP)
standards. Strengthening the regulatory framework and establishing robust
quality control processes for artemisinic acid production would go a long way
in addressing these challenges and ensuring that the market can meet demand for
high-quality, affordable malaria treatments.
High Initial Investment in
Biotechnological Infrastructure
While
biotechnological production of artemisinic acid via microbial fermentation
offers several advantages in terms of cost-effectiveness and sustainability, it
requires significant initial investment in infrastructure, research, and
development. The transition from traditional plant-based extraction methods to
biotechnological processes is capital-intensive, with substantial costs
associated with the establishment of fermentation facilities, purchase of
specialized equipment, and recruitment of skilled labor. For local
manufacturers in Vietnam, the lack of financial resources or access to capital
presents a significant barrier to entry into the biotechnological production
space.
Setting
up biotechnological infrastructure requires advanced expertise in areas such as
genetic engineering, bioprocessing, and industrial microbiology, as well as
significant investment in research and development to optimize production
strains and fermentation processes. Without access to the necessary funding or
technical knowledge, many small- to medium-sized manufacturers may struggle to
compete in the growing market for artemisinic acid. The upfront costs involved
in upgrading production facilities and adopting state-of-the-art technologies
for microbial fermentation may deter potential entrants, leaving the market in
the hands of a few dominant players.
Operating
microbial fermentation systems requires ongoing investments in maintenance,
quality control, and process optimization. Manufacturers must continue to
invest in research to improve yields and reduce costs, which can be a financial
strain for those without access to adequate funding sources. This lack of
capital investment can limit the scalability of local production, making it
challenging for the Vietnamese pharmaceutical industry to meet the growing
demand for artemisinic acid and artemisinin-based therapies. To address this
challenge, the government and private sector must provide financial support and
incentives to encourage investment in the biotechnological infrastructure
required for large-scale production.
Key Market Trends
Advances in Biotechnology and
Sustainable Production Methods
Advances
in biotechnology and sustainable production methods have significantly impacted
the production of artemisinic acid. Biotechnological innovations, such as the
use of genetically modified yeast and other microorganisms for the fermentation
of artemisinic acid, have made it possible to produce artemisinic acid in large
quantities at a lower cost. These advances allow for a more sustainable and
scalable production of artemisinic acid, ensuring a steady and reliable supply
for the pharmaceutical industry. In Vietnam, where there is a strong push for
environmentally friendly and cost-efficient solutions, the adoption of these
biotechnological methods is driving the growth of the artemisinic acid market.
As the production of artemisinic acid becomes more efficient, it will lead to
lower prices for ACTs, making them more accessible to populations in need.
Rising Investment in
Pharmaceutical R&D
The
Vietnamese pharmaceutical industry has seen increasing investment in research
and development (R&D), particularly in the development of new and more
effective malaria treatments. With the growing recognition of the importance of
artemisinic acid in the production of ACTs, many pharmaceutical companies in
Vietnam are investing in R&D to improve the synthesis and production
processes. These investments not only enhance the local production capabilities
but also promote innovations that could make treatments more effective and
accessible. This expanding focus on pharmaceutical R&D, particularly in the
malaria treatment space, is a significant driver for the growth of the
artemisinic acid market, as it leads to higher demand for the precursor
compound.
Segmental Insights
Type Insights
Based on the Type, antimalarial tablets are currently dominating
the market. This dominance is primarily due to their convenience,
cost-effectiveness, and widespread accessibility compared to alternative forms
of treatment like antimalarial injections. Antimalarial tablets are widely
preferred because they offer several practical advantages in comparison to
injectable formulations. They are more user-friendly and can be easily
administered by patients at home, reducing the need for healthcare professionals
to be involved in the treatment process. This is particularly important in
rural and remote areas of Vietnam, where access to healthcare facilities and
trained medical staff may be limited. The simplicity of oral administration
helps ensure that patients are more likely to complete the prescribed treatment
regimen, improving compliance and treatment outcomes. The production and
distribution of antimalarial tablets are more cost-effective compared to
injectable forms, which require more specialized infrastructure and are
generally more expensive to manufacture.
From an economic standpoint, antimalarial
tablets are a more affordable option for both patients and healthcare systems,
particularly in low-income regions. This makes them more accessible to a larger
segment of the population, aligning with the Vietnamese government's efforts to
provide affordable and effective malaria treatments to combat the disease,
which remains a significant public health issue in the country. The use of
artemisinic acid in the synthesis of artemisinin, which is then used in ACTs for
tablet form, makes the production of oral malaria treatments more scalable and
economically viable. As the demand for ACTs continues to grow, driven by the
ongoing prevalence of malaria, the artemisinic acid market is increasingly
centered around the tablet formulation.
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Regional Insights
In the Vietnam Artemisinic Acid Market,
Southern Vietnam was the dominant region in terms of both production and demand
for artemisinic acid. This dominance can be attributed to several factors,
including the region's advanced pharmaceutical manufacturing infrastructure,
higher concentration of research and development (R&D) facilities, and
larger population that drives the demand for antimalarial drugs. Southern
Vietnam, particularly in cities like Ho Chi Minh City, is the economic and
industrial hub of the country. It is home to many of Vietnam’s leading
pharmaceutical companies, which are actively involved in the production of
artemisinic acid and the formulation of artemisinin-based combination therapies
(ACTs). The concentration of pharmaceutical manufacturing plants in the south
provides a significant advantage in terms of scalability and efficiency of
production, enabling local producers to meet the growing demand for malaria
treatments both within Vietnam and in international markets. Ho Chi Minh City serves
as a key export hub, with well-established logistics and distribution channels
that facilitate the movement of artemisinic acid and ACTs to global markets,
especially in malaria-endemic regions.
The availability of resources in Southern
Vietnam also plays a crucial role in its dominance of the artemisinic acid
market. The region benefits from a robust supply chain infrastructure,
including access to ports, raw materials, and skilled labor. As the southern
provinces have a more established industrial base, they can support
biotechnological production processes for artemisinic acid, such as microbial
fermentation, with greater ease. With the growing adoption of these
biotechnological methods, Southern Vietnam is seeing a rise in the local
production of artemisinic acid, further reducing reliance on imported
artemisinic acid or artemisinin, thereby promoting the country’s goal of
self-sufficiency in malaria treatment production.
Southern Vietnam is also home to several key
public health programs aimed at controlling malaria. The region sees a
significant portion of the country’s malaria cases, particularly in areas near
border regions with neighboring countries, such as Cambodia. As a result, the
demand for effective malaria treatments, such as artemisinic acid-based ACTs,
is higher in the south, driving the regional market. Government initiatives in
Southern Vietnam have focused on improving access to affordable malaria treatments
for underserved communities, which in turn supports the growth of the
artemisinic acid market.
Key Market Players
- Bayer Vietnam Ltd.
- DHG Pharmaceutical Joint Stock Company
- Cipla Limited
- Novartis Vietnam Company Limited
- Domesco Medical Import Export Joint Stock Corporation
(DOMESCO)
- OPC Pharmaceutical Joint Stock Company
- Sanofi-Aventis Vietnam
- Mekophar Chemical and Pharmaceutical JSC
- Imexpharm Pharmaceutical Joint Stock Company
- Pymepharco Joint Stock Company
|
By
Type
|
By
Region
|
- Antimalarial
Injection
- Antimalarial
Tablets
|
- Southern
Vietnam
- Northern
Vietnam
- Central
Vietnam
|
Report Scope:
In this report, the
Vietnam Artemisinic Acid Market has
been segmented into the following categories, in addition to the industry trends
which have also been detailed below:
·
Vietnam Artemisinic Acid Market, By Type:
o Antimalarial Injection
o Antimalarial Tablets
- Vietnam Artemisinic Acid Market, By Region:
o Southern Vietnam
o Northern Vietnam
o Central Vietnam
Competitive Landscape
Company
Profiles: Detailed
analysis of the major companies present in the Vietnam Artemisinic Acid Market.
Available Customizations:
Vietnam
Artemisinic Acid Market report with
the given market data, TechSci Research offers customizations according to a
company's specific needs. The following customization options are available for
the report:
Company Information
- Detailed analysis and profiling of
additional market players (up to five).
Vietnam Artemisinic Acid Market is an upcoming report to be released
soon. If you wish an early delivery of this report or want to confirm the date
of release, please contact us at [email protected]