Press Release

Gene Synthesis Market to Grow with a CAGR of 9.76% through 2030F

Technological advancements in the DNA synthesis platforms is expected to drive the Global Gene Synthesis Market growth in the forecast period, 2026-2030F.

 

According to TechSci Research report, “Gene Synthesis Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2030F”, the Global Gene Synthesis Market stood at USD 1.84 Billion in 2024 and is expected to reach USD 2.73 Billion by 2030 with a CAGR of 9.76% during the forecast period.

The declining price of DNA synthesis and sequencing has emerged as a significant driver for the Gene Synthesis market, ushering in a new era of accessibility and innovation in genetic research and biotechnology. This trend is instrumental in reshaping the landscape of gene synthesis and expanding its applications across various domains. First and foremost, the decreasing cost of DNA synthesis services has democratized access to custom-designed genetic constructs. Researchers, laboratories, and organizations with limited budgets can now afford gene synthesis, enabling them to pursue a wider range of scientific studies and biotechnological projects. As a result, the Gene Synthesis market has witnessed increased demand from diverse stakeholders, from academic institutions to startups and multinational corporations. In tandem with DNA synthesis, the affordability of DNA sequencing technologies has also played a crucial role. The decreasing cost of DNA sequencing enables researchers to more readily validate and analyze the synthesized genes, fostering greater confidence in experimental outcomes. This synergy between synthesis and sequencing has created a virtuous cycle, where lower costs in both domains drive greater utilization and innovation in gene synthesis projects. Moreover, the declining prices of DNA synthesis and sequencing have accelerated research and development efforts in genomics and personalized medicine. With reduced financial barriers, scientists can conduct large-scale genomic studies, uncover disease mechanisms, and develop targeted therapies. Gene synthesis is at the forefront of these advances, providing the custom genetic material necessary for such investigations.

Furthermore, as the cost of sequencing genomes continues to drop, the demand for synthesized genes for functional genomics and genome editing studies is on the rise. Researchers use synthesized genes to understand gene function, create disease models, and develop potential treatments, fueling the Gene Synthesis market's growth. In conclusion, the declining prices of DNA synthesis and sequencing are transformative drivers for the Gene Synthesis market. They enable broader access to gene synthesis services, promote innovation, and accelerate scientific discoveries in genomics, synthetic biology, and biotechnology. This affordability trend is likely to continue to shape the future of genetic research and biotechnological applications, fostering a dynamic and inclusive environment for genetic innovation.

 

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The Global Gene Synthesis Market is segmented into method, service, application, end use,  regional distribution, and company.

In the Global Gene Synthesis Market, the Gene & Cell Therapy Development segment dominates due to the increasing adoption of synthetic genes for therapeutic applications. The rising prevalence of genetic disorders, cancers, and chronic diseases has fueled the demand for precise and customized gene sequences used in cell and gene therapy. Advances in genome editing technologies, particularly CRISPR-Cas9, have further strengthened the role of synthetic genes in targeted treatments, driving significant investments from biotechnology and pharmaceutical companies.

Gene synthesis plays a critical role in engineered cell therapies, such as CAR-T cell therapy, where modified genes are introduced into immune cells to enhance their ability to fight diseases like leukemia and lymphoma. Similarly, synthetic genes are essential in gene therapy applications, where they replace faulty genes responsible for inherited disorders, such as cystic fibrosis and sickle cell anemia. The ability to create highly specific and optimized genetic constructs enables greater therapeutic efficacy, reducing risks of adverse effects. Moreover, regulatory approvals and successful clinical trials have encouraged the expansion of gene and cell therapy pipelines. With governments and private investors funding research in regenerative medicine and precision therapeutics, the demand for custom gene synthesis solutions is expected to grow further. While vaccine development and disease diagnosis remain key applications, the Gene & Cell Therapy Development segment leads the market, benefiting from technological advancements and increasing adoption in precision medicine.

Based on region, after North America, Europe stands as the second dominating region in the Global Gene Synthesis Market due to its strong biotechnology and pharmaceutical industry, significant research funding, and well-established regulatory framework supporting synthetic biology innovations. Countries such as Germany, the United Kingdom, and France are at the forefront, driving advancements in gene synthesis for applications in gene therapy, drug development, and precision medicine. One of the primary reasons for Europe’s dominance is the rising adoption of gene synthesis in personalized medicine and rare disease treatments. With a growing focus on regenerative therapies and genetic research, European pharmaceutical companies and research institutions are heavily investing in synthetic biology. The European Union (EU) and national governments provide substantial funding for genomics research, fostering innovation in synthetic DNA technologies.

Additionally, Europe’s strong biomanufacturing infrastructure supports large-scale production of synthetic genes, which are crucial for biopharmaceuticals, vaccine development, and genetic engineering. The region is also witnessing increased collaboration between academic institutions and biotech firms to accelerate gene synthesis advancements. Furthermore, favorable regulatory policies and stringent quality standards ensure that gene synthesis technologies meet ethical and safety requirements, facilitating market growth. While North America remains the largest market, Europe’s technological progress, government support, and increasing adoption of synthetic biology applications position it as the second most dominant region in the Global Gene Synthesis Market.

 

Major companies operating in Global Gene Synthesis Market are:

  • OriGene Technologies, Inc.
  • Integrated DNA Technologies, Inc.
  • ProMab Biotechnologies, Inc.
  • Thermo Fisher Scientific, Inc.
  • ProteoGenix, Inc.
  • Biomatik USA LLC
  • Twist Bioscience
  • Boster Biological Technology
  • Brooks Automation, Inc.
  • Genscript Corporation

 

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“The rising adoption of enzymatic DNA synthesis (EDS) is transforming the Global Gene Synthesis Market by offering a sustainable and efficient alternative to traditional phosphoramidite-based chemical synthesis. EDS utilizes specialized enzymes, such as DNA polymerases and terminal deoxynucleotidyl transferases, to construct DNA strands in a more precise and environmentally friendly manner. Unlike chemical synthesis, which relies on hazardous reagents and produces toxic byproducts, EDS operates in aqueous solutions, significantly reducing its ecological footprint. One of the key advantages of EDS is its ability to synthesize longer and more complex DNA sequences with fewer errors. Traditional methods often struggle with sequences beyond 200 base pairs, requiring labor-intensive assembly techniques. In contrast, enzymatic synthesis enables seamless, high-fidelity construction of extended DNA fragments, accelerating research in genomics, synthetic biology, and personalized medicine. Additionally, EDS enhances production efficiency, offering faster turnaround times by eliminating the need for extensive post-synthesis processing. This speed advantage is crucial for biotech companies and research institutions working on time-sensitive projects, such as vaccine development and gene therapy applications. As EDS technology continues to advance, it is expected to revolutionize DNA synthesis, making it more scalable, cost-effective, and accessible for a wide range of applications in healthcare, agriculture, and industrial biotechnology.,” said Mr. Karan Chechi, Research Director of TechSci Research, a research-based management consulting firm.

Gene Synthesis Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, By Method (Solid-phase Synthesis, Chip-based Synthesis, PCR-based Enzyme Synthesis), By Service (Antibody DNA Synthesis, Viral DNA Synthesis, Others), By Application (Gene & Cell Therapy Development, Vaccine Development, Disease Diagnosis, Others), By End Use (Biotechnology and Pharmaceutical Companies, Academic and Government Research Institutes, Contract Research Organizations), By Region and Competition, 2020-2030F”, has evaluated the future growth potential of Global Gene Synthesis Market and provides statistics & information on market size, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Gene Synthesis Market.

 

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