Press Release

Hunter Syndrome Treatment Market to Grow with a CAGR of 5.02% through 2028

Government support, and the dedication of advocacy groups are expected to drive the Global Hunter Syndrome Treatment Market growth in the forecast period, 2024-2028.

 

According to TechSci Research report, “Hunter Syndrome Treatment Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028”, the Global Hunter Syndrome Treatment Market stood at USD 1055.37 million in 2022 and is anticipated to grow with a CAGR of 5.02% in the forecast period, 2024-2028. This can be attributed to global collaborations. International collaborations between research institutions, pharmaceutical companies, and healthcare organizations have facilitated the exchange of knowledge and expertise in the field of Hunter syndrome treatment. These partnerships have accelerated the development of new therapies and expanded their availability to a wider patient base. Furthermore, efforts to expand access to Hunter syndrome treatments are gaining traction. As awareness increases and more treatment options become available, there is a growing focus on making these therapies accessible to patients in regions with limited healthcare infrastructure. International collaborations and partnerships are helping expand treatment access on a global scale.

The growth of the Hunter Syndrome market was significantly impacted by the COVID-19 pandemic. For instance, a study published in BMC in September 2021 revealed that lysosomal storage diseases (LSDs), including mucopolysaccharidosis II (MPS II or Hunter Syndrome), were negatively affected by COVID-19, leading to disruptions in patients' access to continuous care and therapy. These patients faced a higher risk of contracting COVID-19 compared to the general population. Another study published in BMC in October 2021 indicated that approximately 20% of patients receiving enzyme replacement therapy (ERT) in a hospital setting experienced treatment disruptions due to the pandemic. Consequently, delayed treatment services had a detrimental impact on the market's growth during this period. However, as the pandemic progressed, the market showed signs of recovery, reflected in the increasing number of product developments and approvals. For instance, in January 2021, GC Pharma obtained Japanese manufacturing and marketing approval for Hunterase ICV (intracerebroventricular) injection of 15 mg as a treatment for mucopolysaccharidosis type II (Hunter Syndrome). Several factors are contributing to the market's growth, including rising government initiatives, the introduction of innovative therapies, and robust pipelines for treating Hunter Syndrome. The increasing burden of Hunter diseases and a growing patient population have led to increased investment in research and drug discovery, expected to drive market growth. For example, in September 2021, Takeda Pharmaceuticals entered into an exclusive collaboration and license agreement with JCR Pharmaceuticals to commercialize JR-141, an investigational next-generation recombinant fusion protein designed to treat Hunter Syndrome. This collaboration covers regions outside of the United States, including Canada, Europe, and other areas, excluding Japan and specific Asia-Pacific countries. JCR received an upfront payment for this ex-US license and is eligible for additional development and commercial milestones, as well as tiered royalties on potential sales. Such developments are anticipated to enhance the availability of drugs and therapies in the market, thus bolstering growth over the forecast period.


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Furthermore, the increasing focus on various research and development activities by companies to launch new products for treating Hunter diseases is a contributing factor. For instance, in September 2022, AVROBIO Inc. announced the approval by the UK MHRA, Research Ethics Committee (REC), and Health Research Authority (HRA) to initiate a Phase 1/2 clinical trial of investigational autologous hematopoietic stem cell (HSC) gene therapy for infants diagnosed with neuronopathic mucopolysaccharidosis/Hunter Disease. The market's growth is also supported by the government and organizations' efforts to adopt various strategies, such as collaborations and partnerships, to develop effective drugs and treatment options. An example of this is the partnership between the National MPS Society and Genetic Alliance with Luna in June 2022, aimed at accelerating the development of therapies for Hunter Syndrome patients. In December 2021, these organizations, in collaboration with Takeda Pharmaceutical Company Limited, launched a digital drug discovery community to advance therapeutic interventions for patients with mucopolysaccharidosis type II (MPS II), also known as Hunter Syndrome. The Global Hunter Syndrome Treatment Market is segmented into treatment, end user, regional distribution, and company. Based on its treatment, it is anticipated that the Enzyme Replacement Therapy (ERT) sector will experience substantial growth in the Hunter Syndrome Treatment Market during the projected period. This growth is attributed to several factors, including the increased availability of enzyme replacement therapies, heightened awareness, and less stringent regulations concerning rare diseases. Enzyme replacement therapy (ERT) has become a standard treatment for various rare diseases. It involves replacing the deficient or absent enzyme with a functional recombinant version through intravenous administration. For example, a study published in October 2021 highlighted the effectiveness of pabinafusp alfa in addressing both somatic and CNS symptoms in MPS-II patients, thanks to its ability to traverse the blood-brain barrier to reach central nervous tissues. Consequently, the high efficacy and safety of this innovative enzyme drug are expected to drive its adoption in Hunter Syndrome treatment, thereby boosting market growth.

Based on end user, Hospitals and clinics are poised to maintain their dominant position in the Global Hunter Syndrome Treatment Market throughout the forecast years for several compelling reasons. First and foremost, these healthcare facilities serve as the primary points of access for patients seeking diagnosis, treatment, and ongoing care for Hunter Syndrome. Their established infrastructure, specialized medical teams, and access to cutting-edge medical technologies make hospitals and clinics the go-to destinations for patients and their families. Furthermore, these institutions often collaborate closely with pharmaceutical companies and research organizations to stay at the forefront of treatment advancements, ensuring that patients receive the most effective therapies available. Additionally, hospitals and clinics benefit from their ability to offer comprehensive, multidisciplinary care, addressing not only the physical symptoms of the disease but also the psychological and emotional well-being of patients, which is vital in managing a complex condition like Hunter Syndrome. As a result, their pivotal role in providing holistic care and driving innovation positions them to remain dominant players in the Hunter Syndrome Treatment Market in the foreseeable future.

 

Major companies operating in Global Hunter Syndrome Treatment Market are:

  • Takeda Pharmaceutical Co Ltd
  • F Hoffmann-La Roche AG
  • Abbott Laboratories Inc
  • Johnson & Johnson
  • GSK PLC
  • Bayer AG
  • Novartis AG
  • Pfizer Inc
  • Zimmer Biomet Holdings Inc
  • Sangamo Therapeutics, Inc.

 

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“The future of the Global Hunter Syndrome Treatment Market is filled with promise and innovation. Emerging trends, such as gene therapy, personalized medicine, advanced ERTs, and improved treatment access, are expected to reshape the treatment landscape and offer new hope to individuals living with Hunter syndrome. As researchers, healthcare providers, patient advocacy groups, and pharmaceutical companies collaborate to address the challenges posed by this rare genetic disorder, the outlook for the Hunter Syndrome Treatment Market remains optimistic, driven by a commitment to improving the lives of those affected by this condition,” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based management consulting firm.

Hunter Syndrome Treatment Market By Treatment (Enzyme Replacement Therapy, Hematopoietic Stem Cell Transplant), By End User (Hospitals & Clinics, Ambulatory Care Centers, Others), By Region, By Competition Forecast & Opportunities, 2018-2028F”, has evaluated the future growth potential of Global Hunter Syndrome Treatment Market and provides statistics & information on market size, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Hunter Syndrome Treatment Market.


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