Press Release

RNA Therapy Clinical Trials Market to Grow with a CAGR of 5.73% through 2030

The rising growing prevalence of genetic diseases are expected to drive the Global RNA Therapy Clinical Trials Market in the forecast period 2026-2030.


According to TechSci Research report, “RNA Therapy Clinical Trials Market –Global Industry Size, Share, Trends, Competition, Opportunity and Forecast, 2030F”, the Global RNA Therapy Clinical Trials Market stood at USD 2.87 billion in 2024 and is anticipated to project robust growth in the forecast period with a CAGR of 5.73% through 2030. This phenomenon can be attributed to the cooperative efforts and alliances formed by prominent businesses, which employ a varied strategy to combine the specialized knowledge of each company, thereby enhancing their market presence. Additionally, the recent advancements and developments of niche technologies are expected to propell the growth of Global RNA Therapy Clinical Trials Market by launches of new therapies for different applications, rising government initiatives, etc are expected to rise the growth of Global RNA Therapy Clinical Trials Market.

RNA Therapy Clinical Trials hold significant promise across a spectrum of medical applications, offering innovative approaches to address a wide range of diseases and conditions. The versatility and precision of RNA-based therapies have sparked growing interest and research efforts in various therapeutic areas within the field of clinical trials. RNA Therapy Clinical Trials are revolutionizing cancer treatment by targeting specific genetic mutations or overexpressed genes that drive tumor growth. mRNA vaccines and siRNA therapies are being explored to inhibit the expression of oncogenes, while immunomodulatory RNA therapies aim to enhance the body's immune response against cancer cells. These therapies have the potential to be more selective, less toxic, and more adaptable to tumor heterogeneity compared to traditional chemotherapy. RNA therapies hold promise for treating genetic disorders caused by single gene mutations, such as cystic fibrosis, muscular dystrophy, and Huntington's disease. ASOs can be designed to correct abnormal gene splicing patterns or promote the degradation of disease-causing RNA molecules, offering a potential avenue to address the root causes of these conditions.

RNA Therapy Clinical Trials are exploring treatments for neurodegenerative disorders like Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis (ALS). ASOs and other RNA molecules are designed to target genes associated with disease progression, potentially slowing down or halting degeneration and providing neuroprotection. RNA therapies have garnered attention due to the success of mRNA vaccines against infectious diseases like COVID-19. Beyond vaccines, RNA Therapy Clinical Trials are investigating antiviral siRNA therapies that inhibit viral replication, offering potential treatments for HIV, hepatitis B, and respiratory viruses. Many rare diseases lack effective treatments.

RNA Therapy Clinical Trials are exploring personalized approaches to target specific genetic mutations underlying these conditions. This includes disorders like Duchenne muscular dystrophy, phenylketonuria (PKU), and rare genetic metabolic disorders. RNA therapies are being investigated as potential treatments for cardiovascular diseases such as heart failure and hypercholesterolemia. mRNA therapies can stimulate the production of beneficial proteins, while siRNA therapies can silence genes associated with cholesterol metabolism. RNA-based therapies offer the possibility of modulating immune responses in autoimmune diseases like rheumatoid arthritis, multiple sclerosis, and lupus. By targeting immune-related genes or inflammatory pathways, these therapies aim to restore immune balance and mitigate disease symptoms. However, the preference for appropriate technology, competitive market landscape and growing concerns for human health are expected to slow down the growth of the Global RNA Therapy Clinical Trials Market in the coming years.


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The Global RNA Therapy Clinical Trials Market segmentation is based on Modality, Phase, Therapeutic Areas, Company, and Region.

Based on the therapeutic areas, The rare disease segment is emerging as the fastest-growing category in the RNA Therapy Clinical Trials Market, driven by increasing research initiatives and investments in orphan drug development. With over 7,000 rare diseases affecting millions worldwide and limited treatment options available, there is a strong demand for innovative RNA-based therapies. Governments and regulatory agencies, including the FDA and EMA, are offering incentives such as orphan drug designations, fast-track approvals, and extended market exclusivity, encouraging biotech firms to invest in RNA therapies for rare diseases. Additionally, advancements in mRNA, siRNA, and antisense oligonucleotide technologies have significantly enhanced the feasibility of developing targeted treatments for genetic and metabolic disorders. The rise in strategic partnerships between pharmaceutical companies and biotech startups has further accelerated clinical trials in this segment. For instance, companies like Moderna, Ionis Pharmaceuticals, and Alnylam Pharmaceuticals are actively working on RNA-based treatments for conditions such as spinal muscular atrophy (SMA), Duchenne muscular dystrophy (DMD), and amyloidosis.

Based on the region, The Asia-Pacific region is experiencing the fastest growth in the RNA Therapy Clinical Trials Market, driven by increasing government support, rising investments in biotechnology, and a growing prevalence of rare diseases. Countries like China, Japan, South Korea, and India are rapidly expanding their capabilities in RNA-based drug development through research funding, regulatory advancements, and strategic collaborations. The region benefits from a large patient pool, making it an attractive location for conducting clinical trials at a lower cost compared to Western countries. Additionally, faster regulatory approvals and initiatives like China's regulatory reforms for innovative drugs and Japan's Sakigake fast-track approval system are encouraging global pharmaceutical companies to expand their RNA therapy research in Asia-Pacific.


Some of the major companies operating in the Global RNA Therapy Clinical Trials Market include:

  •  IQVIA Inc.
  • ICON Plc
  • Laboratory Corporation of America Holdings
  • Charles River Laboratories International, Inc.
  • PAREXEL International Corp.
  • Syneos Health
  • Medpace Holdings, Inc.
  • Novotech Inc.
  • PPD Inc.
  • Veristat, LLC.

 

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“North America was expected to dominate in the RNA Therapy Clinical Trials Market due to the presence of many pharmaceutical and biotechnology companies in the region, as well as significant government funding for research and development in the life sciences. Similarly, these technologies are critical for developing new treatments and therapies along with the growing prevalence of chronic diseases such as cancer is expected to create lucrative growth in the market during the forecast period. Also, growing government funding for healthcare infrastructure and a large and rapidly expanding population is expected to drive the growth of the market during the forecast period", said Mr. Karan Chechi, Research Director of TechSci Research, a research-based Global management consulting firm.

"RNA Therapy Clinical Trials Market - Global Industry Size, Share, Trends, Competition, Opportunity, and Forecast, Segmented By Product (Small Molecule API, Small Molecule Drug Product), By Stage Type (Preclinical, Clinical, Commercial), By Customer Type (Pharmaceutical, Biotechnology), By Therapeutic Area (Cardiovascular disease, Oncology, Respiratory disorders, Neurology, Metabolic disorders, Infectious disease, Others), By Region and Competition, 2020-2030F", has evaluated the future growth potential of Global RNA Therapy Clinical Trials Market and provides statistics & information on market size, structure, and future market growth. The report intends to provide innovative market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global RNA Therapy Clinical Trials Market.


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