|
Forecast Period
|
2024-2028
|
|
Market Size (2022)
|
USD 35.88 Billion
|
|
CAGR (2023-2028)
|
12.21%
|
|
Fastest Growing Segment
|
Clinical Diagnostic
|
|
Largest Market
|
North America
|
Market Overview
Global Proteomics Market
has valued at USD 35.88 Billion in 2022 and is anticipated to project impressive
growth in the forecast period with a CAGR of 12.21% through 2028. Proteomics,
the study of proteomes on a large scale, is a crucial field. Proteomics is a
powerful technique utilized for the identification of disease-associated
proteins and the investigation of their production, function, and structure. It
plays a crucial role in the discovery of prognostic markers and the diagnosis
of various diseases, including cancer, infectious illnesses, malaria, and
tuberculosis. Moreover, in the pharmaceutical sector, proteomics is extensively
employed to elucidate the mechanisms of drug action and toxicity. Additionally,
it is commonly applied in the identification and validation of biomarkers. The
proteome is partially influenced by the underlying transcriptome, which
encompasses all messenger RNA molecules in an organism. However, protein
activity is influenced by various factors beyond gene expression levels.
Proteomics has a wide range of applications.
In addition to elucidating
protein-protein interactions and their involvement in metabolic pathways,
proteomics enables the investigation of protein expression patterns, production
and degradation rates, and steady-state abundance. It also allows the study of
post-translational modifications, such as phosphorylation, which can alter
protein function. Moreover, proteomics provides insights into the types of
proteins present in specific cellular compartments, such as the mitochondrion,
and the proteins involved in biological processes like the circadian rhythm,
which regulates the sleep-wake cycle and repeats approximately every 24 hours.
A typical proteomic
experiment aims to gather information about a protein's location,
abundance/turnover, and post-translational modifications. Various
high-throughput technologies have been developed for this purpose, including
mass spectrometry (MS)-based techniques like Tandem-MS, as well as gel-based
techniques such as differential in-gel electrophoresis (DIGE), which are widely
employed in proteomic studies.
Key Market Drivers
Increase
In the Number of Patients Suffering from Cancer
The increasing incidence
of cancer and other disorders is another crucial factor contributing to the
growth of the global proteomics market. With the rising number of cancer cases
worldwide, there is a pressing need for effective treatment options. This has
resulted in extensive research and development in the field of life sciences,
leading to significant advancements and discoveries.
One major breakthrough in
this field is the characterization of human proteins, which has revolutionized
the field of biomedicine. By studying gene expression at the proteome level,
researchers can gain deeper insights into the intricate mechanisms underlying
diseases like cancer. This constant research and development in the field of
proteomics are anticipated to fuel the market's growth to a great extent. Through
the application of proteomics techniques, researchers are able to extract
highly significant biological information that greatly enhances our
understanding of cancer biology. This knowledge can ultimately benefit patients
by improving diagnosis, treatment, and overall patient care.
The continuous
advancements in proteomics research not only help in identifying how proteins
respond in dynamic environments, such as cancer patients, but also pave the way
for the development of personalized medicine. By tailoring treatment plans
based on an individual's unique proteomic profile, healthcare providers can
maximize the effectiveness of therapies and minimize side effects. The
increasing prevalence of cancer, along with the constant progress in proteomics
research, holds immense potential for the global proteomics market. The ability
to extract valuable insights from the proteome level opens up new opportunities
for advancements in diagnosis, treatment, and personalized medicine, ultimately
benefiting patients worldwide.
Increased
Investments In R&D In Proteomics
The National Institutes of
Health (NIH), a renowned institution in the United States, generously
contributed a staggering amount of US$ 37 billion towards groundbreaking
biomedical research. This substantial grant was specifically allocated to
support life sciences research, aiming to deepen our understanding of the
fundamental mechanisms underlying the occurrence of diseases. By investing in
cutting-edge technologies and state-of-the-art facilities, the NIH is
empowering scientists and researchers to explore novel approaches in disease
prevention, diagnosis, and treatment.
The NIH's commitment to
advancing the frontiers of medical knowledge extends beyond the identification
of crucial biomarkers and unraveling the complex interplay of genes and
proteins. It encompasses a multidisciplinary approach that integrates genomics,
proteomics, metabolomics, and other emerging fields to gain comprehensive
insights into disease mechanisms.
Through collaborative
initiatives and partnerships with leading academic institutions and industry
experts, the NIH fosters a vibrant ecosystem of discovery and innovation. This
remarkable investment not only fuels breakthroughs in basic research but also
supports the translation of scientific findings into tangible improvements in
patient care. With its unwavering dedication to scientific excellence, the NIH
is paving the way for advancements in the field of healthcare. By catalyzing
transformative discoveries and nurturing the next generation of scientists, the
NIH plays a pivotal role in shaping the future of medicine and improving human
health and well-being on a global scale.
Rising
Demand for Personalized Medicine
The rising demand for
personalized medicine has spurred a significant increase in the demand for
proteomics, a field of study dedicated to understanding the complex and dynamic
world of proteins within the human body. Personalized medicine represents a paradigm
shift in healthcare, moving away from the one-size-fits-all approach and toward
tailoring medical treatments to an individual's unique genetic makeup,
lifestyle, and disease profile. Proteomics plays a pivotal role in this
transformation by providing valuable insights into the proteome, the complete
set of proteins expressed by an organism.
With the advent of
high-throughput technologies such as mass spectrometry and advanced
bioinformatics tools, proteomics has become a powerful tool in deciphering the
intricate molecular mechanisms underlying diseases. It enables researchers to
identify specific protein markers associated with various medical conditions,
allowing for early disease detection, precise diagnosis, and the development of
targeted therapies. For instance, in oncology, proteomics has facilitated the
discovery of novel biomarkers that aid in predicting a patient's response to
cancer treatments, thereby optimizing therapy choices.
Furthermore, proteomics is
instrumental in understanding the intricacies of drug interactions with
proteins, paving the way for the development of personalized drug regimens. By
analyzing an individual's protein profile, healthcare providers can determine
the most effective and safest medications, minimizing adverse effects and
improving overall treatment outcomes.
Technological
Advancements
The advancement of
cutting-edge tools that significantly enhance the productivity, throughput, and
speed of biological research is poised to revolutionize the field and foster
rapid market expansion. State-of-the-art 2-D electrophoresis protein analyzers,
equipped with advanced algorithms and innovative technologies, offer an
unparalleled ability to accurately analyze complex protein samples.
These advanced analyzers
not only provide high precision and efficiency, but they also empower
researchers with a comprehensive suite of features. With their advanced image
analysis capabilities, researchers can precisely identify and quantify
proteins, even in low-abundance samples. The integration of innovative
automation technologies allows for seamless sample handling and processing,
minimizing human error and maximizing throughput. Additionally, the analyzers
are equipped with intuitive software interfaces that streamline data analysis
and visualization, enabling researchers to uncover valuable insights from their
experiments more quickly.
By empowering researchers
to uncover valuable insights and accelerate breakthrough discoveries, these
advanced analyzers have the potential to propel the field of biological
research to new heights. With exceptional precision and efficiency, they pave
the way for further growth and innovation in the industry, opening up exciting
possibilities for scientists and researchers worldwide. With their ability to
handle complex protein samples and provide detailed analysis, these analyzers
are revolutionizing the way biological research is conducted, enabling
scientists to delve deeper into the intricacies of life at the molecular level.
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Key Market
Challenges
Expensive
Instruments
The need for a longer
period of time in laboratories increases the cost of treatment. This is
primarily due to the expensive instruments and reagents used in the process,
which limits the use of this technology in developing nations. One of the most
commonly used methods in proteomics is X-ray crystallography. This method
involves protein expression, gene cloning, protein crystallization, and
purification. However, these procedures are time-consuming, resulting in higher
costs. As a result, the adoption of these procedures in developing nations is
limited. This presents a significant challenge to the growth of the market and
will continue to hinder its progress in the long run.
To overcome this obstacle
and promote market growth in developing nations, it is crucial to expand the
accessibility and affordability of these technologies. By doing so, more
laboratories and research institutions in these regions will be able to utilize
these advanced techniques to study proteins and contribute to scientific
advancements. This, in turn, can lead to improved healthcare solutions, better
understanding of diseases, and the development of targeted therapies.
Furthermore, addressing
the cost issue can also encourage collaborations between developed and
developing nations in the field of proteomics. By sharing resources, knowledge,
and expertise, it becomes possible to overcome the financial limitations and accelerate
the progress of research and innovation. This collaborative approach can create
a more inclusive and globally connected scientific community, where
breakthroughs in proteomics are not limited by economic constraints.
The longer time required
and higher costs associated with proteomic research in laboratories pose
challenges to its widespread adoption in developing nations. However, by
expanding the accessibility, affordability, and fostering international
collaborations, we can overcome these obstacles and promote market growth in
these regions. This will not only advance scientific knowledge but also
contribute to improving healthcare outcomes for people around the world.
Experimental
Challenges in Protein Structure Determination
One of the major
challenges hindering the growth of the global proteomics market is the
experimental difficulties associated with determining protein structures.
Protein structure determination is a complex and intricate process that often
requires the utilization of multiple techniques and expertise. Current methods,
such as X-ray crystallography and NMR spectroscopy, although widely used, have
their limitations and may not always yield successful results. The
determination of protein structures becomes even more challenging when dealing
with large, multi-domain proteins, membrane proteins, and proteins with
flexible regions.
In addition to these
challenges, the detection of post-translational modifications (PTMs) and the
significant cost and time required for protein structure determination pose
significant obstacles to the advancement of the field. The identification and
characterization of PTMs play a crucial role in understanding protein function
and regulation, but their detection can be technically demanding and
time-consuming.
To overcome these
challenges and foster the growth of the proteomics market, it is imperative to
develop new techniques, improve existing methods, and encourage
interdisciplinary collaboration. The inherent instability and flexibility of
proteins present challenges that extend across various aspects of proteomics,
impeding the market's progress in the forecast period. By addressing these
experimental challenges and advancing our understanding of protein structures
and functions, we can unlock new opportunities for innovation and drive the
future development of the proteomics field.
Key Market Trends
Emergence
Of Label-Free Quantification Techniques
The emergence of
label-free quantification techniques is a major trend in the market. The global
proteomics market has witnessed notable trends, including the rise of
label-free quantification techniques. Label-free quantification, a
revolutionary approach in proteomics, utilizes mass spectrometry-based methods
to accurately measure proteins without the need for chemical or isotopic
labels. By eliminating the use of labels, this technique offers enhanced
accuracy, reproducibility, and cost-effectiveness, making it an attractive
option for researchers. Moreover, label-free quantification enables the
analysis of larger sample sizes, allowing for more comprehensive proteomic
studies. Additionally, this approach avoids potential artifacts that may arise
from labeling interference, ensuring the integrity of the protein
quantification results. As the demand for high-throughput, reliable, and
cost-effective proteomic analysis continues to grow, the adoption of label-free
quantification techniques is expected to increase rapidly in the coming years,
revolutionizing the field of proteomics and advancing our understanding of
complex biological systems.
Integration
of Artificial Intelligence
Artificial intelligence in
proteomics is a well-known and rapidly growing trend in the field. The use of artificial
intelligence in proteomics applications is already making significant
advancements in the field of drug development. By considering how and why
specific proteins interact, researchers can better understand the complexities
of cell biology and determine the potential therapeutic or harmful effects of
new medications.
In addition to the impact
of artificial intelligence, there are several other market trends that are
driving the expansion of the proteome market. The rise in drug discovery
efforts, fueled by advancements in technology, is leading to the development of
innovative proteomic technologies and techniques. Nano proteomics, in
particular, is gaining increasing significance as it allows for the analysis of
proteins at the nanoscale, providing valuable insights into their structure and
function.
Furthermore, the
advancement of proteomic technology is enabling new applications in various
fields, including diagnostics, personalized medicine, and biomarker discovery.
These advancements are expected to further accelerate the growth of the
proteome market over the forecast period, opening up new opportunities for
research and development in the field of proteomics.
Segmental Insights
Product Insights
The reagents & assays segment accounted for the
highest share in the global revenue in 2022. This segment is expected to
experience the fastest growth rate during the projected period. The significant
growth can be attributed to the extensive use of reagents & consumables,
kits, chemicals, and strips for the examination of various biological samples.
These resources are widely utilized in academic institutions, research labs,
and other establishments, thereby driving the demand for reagents &
consumables and fueling the growth of this segment.
Moreover, the market growth is further supported by
the technological advancements in advanced instruments, such as 2-D
electrophoresis protein analyzers. These innovative instruments enhance the
speed, efficiency, and throughput of biological research, providing researchers
with valuable tools to conduct their experiments and investigations. With such
advancements, the market is expected to witness a positive growth trajectory in
the coming years.
Technology Insights
Based on the latest advancements in technologies, the
proteomics market is broadly segmented into various techniques and tools that
enable comprehensive protein analysis. These include Spectroscopy, Microarray
instruments, Chromatography, X-ray crystallography, Protein Microarrays, and
Electrophoresis. Among these, spectroscopy emerged as the leading technique in
2022, capturing the largest share of the proteomics market for instrumentation
technologies.
The dominance of spectroscopy can be attributed to its
widespread utilization in studying proteins and gaining insights into their
structures, interactions, and functions. Spectroscopic techniques offer
valuable information about the properties of proteins, including their
secondary and tertiary structures, conformational changes, and ligand binding.
By leveraging spectroscopy, researchers and scientists can delve deeper into
the intricacies of protein behavior, facilitating advancements in various fields,
such as drug discovery, diagnostics, and personalized medicine.
The continuous evolution and innovation in
spectroscopy, along with its ability to provide detailed and precise protein
analysis, make it an indispensable tool in the proteomics field. As researchers
strive to unlock the mysteries of complex biological systems at the molecular
level, spectroscopy remains a vital component in their quest for knowledge and
breakthrough discoveries.
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Regional Insights
North America emerged as
the dominant player, generating substantial revenue throughout the projected
period. The growth of omics research, the need for reliable data
reproducibility tools, and the focus on personalized treatments all contribute
to this trend. Additionally, the market's expansion is facilitated by strategic
alliances and collaborations among key regional enterprises. A notable example
is the partnership between Symphogen and Thermo Fisher Scientific Inc., aimed
at developing standardized platform methods for the efficient characterization
and quality monitoring of complex therapeutic proteins.
The Asia-Pacific region is
projected to experience the highest growth rate between 2024 and 2028. This
growth can be attributed to several factors, including the outsourcing of
proteomics-based projects, both public and private funding for proteomics research
and development, favorable government regulations, increasing adoption of
proteomics leading to a rise in target disease prevalence, and an aging
population. For example, in November, the University of Hyderabad received a
million-dollar grant from the Department of Biotechnology of the Indian
Government to study the tomato proteome. Government initiatives supporting
proteomics research play a pivotal role in driving the growth of the
Asia-Pacific market.
Recent Developments
- Bruker Corporation launched the nanoElute 2 nano-LC in
August 2022, along with MetaboScape and TASQ 2023 software to support
fluxomics. They also introduced the latest advancements in PaSER intelligent
acquisition, aiming to enhance research in protein-protein interactions (PPIs)
and metaproteomics applications.
- In February 2021, Agilent Technologies Inc. unveiled
the Agilent Dako SARS-CoV-2 IgG Enzyme-Linked Immunosorbent Assay (ELISA) kit.
This kit is designed for the qualitative detection of immunoglobulin G (IgG)
antibodies to SARS-CoV-2 in human serum or plasma.
- In December 2020, Thermo Fisher Scientific acquired
Phitonex, Inc. This acquisition allows Thermo Fisher to expand its flow
cytometry and imaging multiplexing capabilities, meeting the evolving needs of
customers in protein and cell analysis research.
Key Market Players
- Illumina, Inc.
- Thermo Fisher Scientific
Company Profile
- Bruker Corporation
- Promega Corporation
- Agilent Technologies Inc.
Company Profile
- Merck KGaA.
- Bio-Rad Laboratories, Inc.
Company Profile
- Danaher Corporation
Company Profile
- F Hoffmann-La Roche Ltd.
- Luminex Corporation
|
By
Product
|
By
Technology
|
By
Application
|
By Type
|
By
End User
|
By
Region
|
- Reagents
& Assays
- Instruments
- Software
& Services
|
- Spectroscopy
- Microarray
instruments
- Chromatography
- X-ray
crystallography
- Protein
Microarrays
- Electrophoresis
|
- Clinical
Diagnostic
- Drug
Discovery
- Diagnostic
Biomarker Discovery
- Others
|
- Expression
- Functional
- Structural
- Computational
|
- Pharmaceutical
and Biotechnology Companies
- Research
Institutes
- CROs
|
- North
America
- Europe
- Asia
Pacific
- South
America
- Middle
East & Africa
|
Report
Scope:
In this report, the Global
Proteomics Market has been segmented into the following categories, in addition
to the industry trends which have also been detailed below:
- Proteomics Market, By Product:
o
Reagents & Assays
o
Instruments
o
Software &
Services
- Proteomics Market, By Technology:
o
Spectroscopy
o
Microarray
instruments
o
Chromatography
o
X-ray crystallography
o
Protein Microarrays
o
Electrophoresis
- Proteomics Market, By Application:
o
Clinical Diagnostic
o
Drug Discovery
o
Diagnostic Biomarker
Discovery
o
Others
- Proteomics Market, By Type:
o
Expression
o
Functional
o
Structural
o
Computational
- Proteomics Market, By End User:
o
Pharmaceutical and
Biotechnology Companies
o
Research Institutes
o
CROs
- Proteomics Market, By Region:
o North
America
§ United
States
§ Canada
§ Mexico
o Europe
§ France
§ United
Kingdom
§ Italy
§ Germany
§ Spain
o Asia-Pacific
§ China
§ India
§ Japan
§ Australia
§ South
Korea
o South America
§ Brazil
§ Argentina
§ Colombia
o Middle
East & Africa
§ South
Africa
§ Saudi
Arabia
§ UAE
§ Kuwait
§ Turkey
§ Egypt
Competitive
Landscape
Company
Profiles: Detailed analysis of the major companies present in
the Global Proteomics Market.
Available
Customizations:
Global Proteomics market
report with the given market data, Tech Sci Research offers customizations
according to a company's specific needs. The following customization options
are available for the report:
Company
Information
- Detailed
analysis and profiling of additional market players (up to five).
Global Proteomics Market is an upcoming report to be
released soon. If you wish an early delivery of this report or want to confirm
the date of release, please contact us at [email protected]