Pain Patch Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented By Product Type (Non-Opioid Patches, Opioid Patches), By Type (Prescription Medicines, OTC Medicines),By Distribution Channel (Hospital Pharmacies, Drug Stores and Retail Pharmacies, Online Providers), By Region and Competition

Industry : Healthcare
Pages : NA
Published Date : NA

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Report Description

Forecast Period	2024-2028
Market Size (2022)	USD 4.95 Billion
CAGR (2023-2028)	4.25%
Fastest Growing Segment	OTC Medicines
Largest Market	North America

Market Overview

Global Pain Patch Market has valued at USD 4.95 Billion in 2022 and is anticipated to project impressive growth in the forecast period with a CAGR of 4.25% through 2028. Pain patches have emerged as a convenient and effective solution for managing various forms of pain, offering an alternative to traditional oral medications. These patches deliver localized relief through transdermal drug delivery systems, making them an attractive option for individuals seeking comfort and convenience in pain management. The global pain patch market has experienced substantial growth in recent years, driven by factors such as the increasing prevalence of chronic pain conditions, an aging population, and a growing demand for non-invasive pain management solutions. Chronic pain conditions, such as arthritis, back pain, neuropathic pain, and fibromyalgia, are on the rise globally. Pain patches offer a targeted approach to manage chronic pain without the side effects associated with oral medications, contributing to their popularity. As the global population ages, there is a higher incidence of age-related pain conditions. Elderly individuals often prefer pain patches as they are easy to apply and provide sustained relief without the need for frequent dosing. Pain patches are non-invasive and offer a discreet way to manage pain without the need for injections or pills. This appeals to patients looking for alternative methods of pain relief. Ongoing research and development in drug delivery technologies have led to more efficient and long-lasting pain patch formulations. These patches can now deliver a variety of medications, including opioids, non-steroidal anti-inflammatory drugs (NSAIDs), and muscle relaxants. Pharmaceutical companies and medical device manufacturers are continuously expanding their pain patch product portfolios. This includes the development of patches for specific pain types and the introduction of innovative features such as smart patches that monitor and adjust drug delivery based on the patient's needs.

Key Market Drivers

Rising Prevalence of Chronic Pain is Driving the Global Pain Patch Market

Chronic pain is a widespread and debilitating condition that affects millions of people worldwide, significantly impacting their quality of life. As the global population continues to age and the incidence of chronic conditions such as arthritis, back pain, and neuropathy rises, the demand for effective pain management solutions is on the rise. One such solution that is gaining traction in the healthcare industry is the pain patch. These transdermal patches are becoming increasingly popular due to their convenience, effectiveness, and ability to provide consistent pain relief.

Chronic pain is a complex condition that can result from various causes, including injury, illness, surgery, or underlying health conditions. Unlike acute pain, which usually subsides once the underlying issue is resolved, chronic pain persists for an extended period, often lasting months or even years. It can lead to physical disability, emotional distress, and decreased productivity, making it a significant healthcare challenge. According to the Global Burden of Disease Study 2019, chronic pain affects over 1.5 billion people worldwide, with back pain being the most common type. The prevalence of chronic pain is expected to rise as the global population ages, and lifestyle factors contribute to the development of conditions like osteoarthritis, diabetes, and obesity. With this increasing prevalence, there is a growing need for effective, long-term pain management solutions.

Pain patches provide controlled and sustained release of medication, ensuring a steady blood concentration and consistent pain relief. This method reduces the risk of overdose or underdosing, which can occur with oral medications. Pain patches are easy to apply and require minimal effort on the part of the patient. They can be worn discreetly and do not interfere with daily activities, allowing individuals to maintain their quality of life. Transdermal delivery bypasses the gastrointestinal system, reducing the risk of stomach upset and other side effects commonly associated with oral pain medications. Chronic pain often requires long-term medication management. Pain patches promote better adherence to treatment regimens, as patients do not need to remember to take pills multiple times a day. Pain patches are available for various types of pain, including opioids, non-steroidal anti-inflammatory drugs (NSAIDs), and lidocaine. This diversity allows healthcare providers to tailor treatment plans to individual patient needs.

Growing Aging Population is Driving the Global Pain Patch Market

The global healthcare landscape is undergoing a significant transformation, driven in large part by the aging population. As life expectancy continues to rise, so too does the prevalence of chronic health conditions that often result in chronic pain. In response to this growing demand for pain relief solutions, the global pain patch market is experiencing remarkable growth. The world's population is aging at an unprecedented rate. According to the World Health Organization (WHO), by 2050, the global population aged 60 and older is expected to reach 2 billion, nearly double the number in 2015. This demographic shift can be attributed to declining birth rates and increased life expectancy, thanks to advancements in healthcare and living conditions. While this aging population trend is a testament to our progress, it also brings its own set of challenges.

To address the need for effective pain management among the aging population, the global pain patch market has seen substantial growth. Pain patches are transdermal patches infused with medications designed to provide long-lasting relief from various types of pain. They offer several advantages over traditional oral pain medications, including reduced side effects, improved patient compliance, and controlled release of medication over an extended period.

With more seniors experiencing chronic pain, there is a growing demand for effective pain relief solutions. Pain patches offer a convenient and non-invasive way to manage pain, making them an attractive option for older adults. Advances in patch technology have led to the development of more sophisticated and efficient pain patches. These patches can deliver a wide range of medications, including opioids, non-steroidal anti-inflammatory drugs (NSAIDs), and muscle relaxants, tailored to individual patient needs. Pain patches are considered safer for older adults, as they minimize the risk of gastrointestinal issues and overdose associated with oral medications. Additionally, they are easy to apply and provide continuous pain relief for several days. Aging populations also mean increased healthcare infrastructure, including clinics, hospitals, and long-term care facilities, which contribute to the distribution and adoption of pain patches. As awareness about pain patches grows among healthcare professionals and patients, more individuals are opting for this non-invasive pain management option.

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Key Market Challenges

Regulatory Hurdles

One of the primary challenges for the pain patch market is navigating the complex web of regulatory requirements. Pain patches are considered medical devices or drug delivery systems, and they must meet stringent regulatory standards set by health authorities like the FDA (U.S. Food and Drug Administration) and the EMA (European Medicines Agency). Obtaining regulatory approvals can be a lengthy and expensive process, often delaying product launches and increasing development costs. Manufacturers must demonstrate the safety, efficacy, and quality of their pain patches, which can be particularly challenging for novel formulations or drug combinations.

Intellectual Property Issues

The pain patch market is highly competitive, with multiple companies vying for market share. This competitive landscape can lead to intellectual property disputes, as companies seek to protect their innovations and challenge the patents of competitors. These legal battles can tie up resources and hinder the introduction of new pain patch products to the market.

Patient Adherence

Patient adherence is a crucial factor in the success of pain patch therapy. While pain patches offer the advantage of continuous medication delivery, patients may still struggle with adherence due to issues such as skin irritation, discomfort, or difficulty in keeping the patch in place. Ensuring patient education and addressing these challenges is essential to maximize the effectiveness of pain patches.

Safety Concerns

Safety is paramount in the healthcare industry, and pain patches are no exception. There have been instances of adverse events associated with pain patches, such as skin reactions, overdose, or misuse. Manufacturers must invest in rigorous testing and safety measures to mitigate these risks. Furthermore, the risk of accidental exposure, especially in households with children or pets, remains a concern.

Pricing and Reimbursement

The pricing of pain patches can be a significant challenge, particularly in regions with a strong focus on cost containment in healthcare. Reimbursement policies and negotiations with insurance companies can affect the accessibility of pain patches for patients. Striking a balance between affordability and profitability while maintaining product quality is a delicate task for manufacturers.

Competition from Alternative Therapies

Pain management is a dynamic field with various alternative therapies, including oral medications, injections, physical therapy, and even emerging technologies like neuromodulation devices. The pain patch market faces competition not only from other pharmaceuticals but also from these alternative treatment options. To stay competitive, pain patch manufacturers must continually innovate and differentiate their products.

Key Market Trends

Technological Advancements

The global healthcare industry is witnessing a significant transformation, driven by rapid technological advancements and a growing emphasis on patient-centric solutions. One notable area where these changes are manifesting is in the pain management sector. Traditional methods of pain relief, such as oral medications, injections, and physical therapy, are now being complemented and, in some cases, replaced by innovative solutions like pain patches. These patches are gaining traction in the global market due to their convenience, effectiveness, and advancements in their technology.

Microneedle pain patches are a relatively recent innovation that involves tiny needles on the patch's surface. These needles painlessly penetrate the skin, delivering medication directly to the bloodstream. This technology offers faster relief and precise dosing, making it a promising solution for various types of pain management. The integration of smart technology into pain patches is revolutionizing pain management. These patches can monitor vital signs, track medication adherence, and provide real-time data to healthcare providers and patients. The ability to customize pain relief regimens and collect data for research purposes makes smart pain patches a significant advancement in the industry. Technological advancements have allowed for the development of more stable and long-lasting drug formulations. This ensures that the medication is released consistently over an extended period, reducing the need for frequent patch replacements and providing more continuous pain relief. The adhesives used in pain patches have improved significantly. They are now designed to adhere securely to the skin while being gentle enough to avoid causing irritation. These advancements contribute to the comfort and effectiveness of pain patches.

Segmental Insights

Product Type Insights

Based on the category of Product Type, Non-Opioid Patches emerged as the dominant player in the global market for Pain Patch in 2022. Non-opioid pain patches have evolved significantly in recent years, making them a more attractive option for both patients and healthcare providers. Non-opioid pain patches utilize transdermal delivery systems to release medication through the skin and into the bloodstream gradually. This allows for controlled and sustained pain relief over an extended period, reducing the need for frequent dosing. Manufacturers are now offering customized formulations of non-opioid pain patches to address various types of pain, such as neuropathic pain, musculoskeletal pain, and inflammatory pain. This tailoring of patches to specific pain types enhances their effectiveness. Non-opioid pain patches often come with fewer side effects compared to oral medications. This is particularly important for patients who may be sensitive to the gastrointestinal or central nervous system side effects of opioids or NSAIDs.

Type Insights

The Prescription Medicines segment is projected to experience rapid growth during the forecast period. Prescription medicines used in pain patches are subject to strict regulation and oversight. Healthcare professionals carefully assess patients' medical histories, ensuring that these powerful medications are prescribed appropriately. This reduces the risk of misuse and dependency, which is a significant concern with certain pain medications, especially opioids. One of the key reasons behind the dominance of prescription medicines in the pain patch market is the ability to deliver precise and targeted treatment. Pain patches can be placed directly over the affected area, allowing the medication to work locally. This approach minimizes systemic side effects and maximizes pain relief, addressing the root cause of the pain more effectively than oral medications, which are distributed throughout the body.

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Regional Insights

North America emerged as the dominant player in the global Pain Patch market in 2022, holding the largest market share in terms of value. The region boasts a robust pharmaceutical and biotech sector, supported by significant investments in research and development. North American companies have been at the forefront of developing cutting-edge pain patch technologies, including advanced drug delivery systems and transdermal formulations. North America's stringent regulatory framework ensures that pain patches meet high safety and efficacy standards. The U.S. Food and Drug Administration (FDA) and Health Canada play crucial roles in approving and monitoring these products, instilling confidence in patients and healthcare professionals. The growing awareness of pain management options and the risks associated with traditional pain medications have driven consumers and healthcare providers to explore alternative solutions like pain patches. This heightened awareness has spurred demand for these products in the region.

Recent Developments

In August 2022, Sorrento Therapeutics Inc. made an announcement regarding the inclusion of their product, ZTlido (a topical lidocaine system with a 1.8% concentration), into one of the largest National Pharmacy Benefit Managers (PBMs) and a national health plan. This decision effectively broadened the coverage to encompass 30 million individuals. Furthermore, Scilex will maintain its collaboration with them to gain access to an additional 20 million potential beneficiaries.
In January 2021, Hisamitsu Pharmaceutical Co., Inc. declared that it had received approval for modifying certain aspects of the previously approved specifications for their new transdermal analgesic anti-inflammatory patches, known as "Mohrus Paps XR 120 mg and 240 mg." This adjustment aimed to alleviate the irritation caused by the current additives.
In August 2020, Amneal Pharmaceuticals, Inc., a pharmaceutical manufacturing firm, disclosed that it had obtained Abbreviated New Drug Application (ANDA) approval from the U.S. Food and Drug Administration (FDA) for a generic variant of Lidocaine Patch, 5%, which serves as an alternative to the Lidoderm Patch, 5%, used in the treatment of post-herpetic neuralgia.

Key Market Players

NEXGEL Advanced Hydrogel Solutions
Viatris Inc.
Johnson and Johnson
Teva Pharmaceutical Industries Ltd.
Sorrento Therapeutics Inc.
Hisamitsu Pharmaceutical Co.,Inc.
Endo International plc.
Purdue Pharma L.P.
Amneal Pharmaceuticals LLC
Grunenthal

By Product Type	By Type	By Distribution Channel	By Region
Non-Opioid Patches Opioid Patches	Prescription Medicines OTC Medicines	Hospital Pharmacies Drug Stores and Retail Pharmacies Online Providers	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Pain Patch Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Pain Patch Market, By Product Type:

o Non-Opioid Patches

o Opioid Patches

Pain Patch Market, By Type:

o Prescription Medicines

o OTC Medicines

Pain Patch Market, By Distribution Channel:

o Hospital Pharmacies

o Drug Stores and Retail Pharmacies

o Online Providers

Pain Patch Market, By Region:

o North America

§ United States

§ Canada

§ Mexico

o Europe

§ France

§ United Kingdom

§ Italy

§ Germany

§ Spain

o Asia-Pacific

§ China

§ India

§ Japan

§ Australia

§ South Korea

o South America

§ Brazil

§ Argentina

§ Colombia

o Middle East & Africa

§ South Africa

§ Saudi Arabia

§ UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Pain Patch Market.

Available Customizations:

Global Pain Patch market report with the given market data, Tech Sci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

Detailed analysis and profiling of additional market players (up to five).

Global Pain Patch Market is an upcoming report to be released soon. If you wish an early delivery of this report or want to confirm the date of release, please contact us at [email protected]

Table of content

1. Product Overview

1.1. Market Definition

1.2. Scope of the Market

1.2.1. Markets Covered

1.2.2. Years Considered for Study

1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study

2.2. Baseline Methodology

2.3. Key Industry Partners

2.4. Major Association and Secondary Sources

2.5. Forecasting Methodology

2.6. Data Triangulation & Validations

2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market

3.2. Overview of Key Market Segmentations

3.3. Overview of Key Market Players

3.4. Overview of Key Regions/Countries

3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Pain Patch Market Outlook

5.1. Market Size & Forecast

5.1.1. By Value

5.2. Market Share & Forecast

5.2.1. By Product Type (Non-Opioid Patches, Opioid Patches)

5.2.2. By Type (Prescription Medicines, OTC Medicines)

5.2.3. By Distribution Channel (Hospital Pharmacies, Drug Stores and Retail Pharmacies, Online Providers)

5.2.4. By Region

5.2.5. By Company (Shares of Top 5 Market Players)

5.3. Market Map

5.3.1. By Product Type

5.3.2. Type

5.3.3. By Distribution Channel

5.3.4. By Region

6. North America Pain Patch Market Outlook

6.1. Market Size & Forecast

6.1.1. By Value

6.2. Market Share & Forecast

6.2.1. By Product Type

6.2.2. By Type

6.2.3. By Distribution Channel

6.2.4. By Country

6.2.4.1. United States Pain Patch Market Outlook

6.2.4.1.1. Market Size & Forecast

6.2.4.1.1.1. By Value

6.2.4.1.2. Market Share & Forecast

6.2.4.1.2.1. By Product Type

6.2.4.1.2.2. By Type

6.2.4.1.2.3. By Distribution Channel

6.2.4.2. Canada Pain Patch Market Outlook

6.2.4.2.1. Market Size & Forecast

6.2.4.2.1.1. By Value

6.2.4.2.2. Market Share & Forecast

6.2.4.2.2.1. By Product Type

6.2.4.2.2.2. By Type

6.2.4.2.2.3. By Distribution Channel

6.2.4.3. Mexico Pain Patch Market Outlook

6.2.4.3.1. Market Size & Forecast

6.2.4.3.1.1. By Value

6.2.4.3.2. Market Share & Forecast

6.2.4.3.2.1. By Product Type

6.2.4.3.2.2. By Type

6.2.4.3.2.3. By Distribution Channel

7. Europe Pain Patch Market Outlook

7.1. Market Size & Forecast

7.1.1. By Value

7.2. Market Share & Forecast

7.2.1. By Product Type

7.2.2. By Type

7.2.3. By Distribution Channel

7.2.4. By Country

7.2.4.1. France Pain Patch Market Outlook

7.2.4.1.1. Market Size & Forecast

7.2.4.1.1.1. By Value

7.2.4.1.2. Market Share & Forecast

7.2.4.1.2.1. By Product Type

7.2.4.1.2.2. By Type

7.2.4.1.2.3. By Distribution Channel

7.2.4.2. Germany Pain Patch Market Outlook

7.2.4.2.1. Market Size & Forecast

7.2.4.2.1.1. By Value

7.2.4.2.2. Market Share & Forecast

7.2.4.2.2.1. By Product Type

7.2.4.2.2.2. By Type

7.2.4.2.2.3. By Distribution Channel

7.2.4.3. United Kingdom Pain Patch Market Outlook

7.2.4.3.1. Market Size & Forecast

7.2.4.3.1.1. By Value

7.2.4.3.2. Market Share & Forecast

7.2.4.3.2.1. By Product Type

7.2.4.3.2.2. By Type

7.2.4.3.2.3. By Distribution Channel

7.2.4.4. Italy Pain Patch Market Outlook

7.2.4.4.1. Market Size & Forecast

7.2.4.4.1.1. By Value

7.2.4.4.2. Market Share & Forecast

7.2.4.4.2.1. By Product Type

7.2.4.4.2.2. By Type

7.2.4.4.2.3. By Distribution Channel

7.2.4.5. Spain Pain Patch Market Outlook

7.2.4.5.1. Market Size & Forecast

7.2.4.5.1.1. By Value

7.2.4.5.2. Market Share & Forecast

7.2.4.5.2.1. By Product Type

7.2.4.5.2.2. By Type

7.2.4.5.2.3. By Distribution Channel

8. Asia Pacific Pain Patch Market Outlook

8.1. Market Size & Forecast

8.1.1. By Value

8.2. Market Share & Forecast

8.2.1. By Product Type

8.2.2. By Type

8.2.3. By Distribution Channel

8.2.4. By Country

8.2.4.1. China Pain Patch Market Outlook

8.2.4.1.1. Market Size & Forecast

8.2.4.1.1.1. By Value

8.2.4.1.2. Market Share & Forecast

8.2.4.1.2.1. By Product Type

8.2.4.1.2.2. By Type

8.2.4.1.2.3. By Distribution Channel

8.2.4.2. India Pain Patch Market Outlook

8.2.4.2.1. Market Size & Forecast

8.2.4.2.1.1. By Value

8.2.4.2.2. Market Share & Forecast

8.2.4.2.2.1. By Product Type

8.2.4.2.2.2. By Type

8.2.4.2.2.3. By Distribution Channel

8.2.4.3. South Korea Pain Patch Market Outlook

8.2.4.3.1. Market Size & Forecast

8.2.4.3.1.1. By Value

8.2.4.3.2. Market Share & Forecast

8.2.4.3.2.1. By Product Type

8.2.4.3.2.2. By Type

8.2.4.3.2.3. By Distribution Channel

8.2.4.4. Japan Pain Patch Market Outlook

8.2.4.4.1. Market Size & Forecast

8.2.4.4.1.1. By Value

8.2.4.4.2. Market Share & Forecast

8.2.4.4.2.1. By Product Type

8.2.4.4.2.2. By Type

8.2.4.4.2.3. By Distribution Channel

8.2.4.5. Australia Pain Patch Market Outlook

8.2.4.5.1. Market Size & Forecast

8.2.4.5.1.1. By Value

8.2.4.5.2. Market Share & Forecast

8.2.4.5.2.1. By Product Type

8.2.4.5.2.2. By Type

8.2.4.5.2.3. By Distribution Channel

9. South America Pain Patch Market Outlook

9.1. Market Size & Forecast

9.1.1. By Value

9.2. Market Share & Forecast

9.2.1. By Product Type

9.2.2. By Type

9.2.3. By Distribution Channel

9.2.4. By Country

9.2.4.1. Brazil Pain Patch Market Outlook

9.2.4.1.1. Market Size & Forecast

9.2.4.1.1.1. By Value

9.2.4.1.2. Market Share & Forecast

9.2.4.1.2.1. By Product Type

9.2.4.1.2.2. By Type

9.2.4.1.2.3. By Distribution Channel

9.2.4.2. Argentina Pain Patch Market Outlook

9.2.4.2.1. Market Size & Forecast

9.2.4.2.1.1. By Value

9.2.4.2.2. Market Share & Forecast

9.2.4.2.2.1. By Product Type

9.2.4.2.2.2. By Type

9.2.4.2.2.3. By Distribution Channel

9.2.4.3. Colombia Pain Patch Market Outlook

9.2.4.3.1. Market Size & Forecast

9.2.4.3.1.1. By Value

9.2.4.3.2. Market Share & Forecast

9.2.4.3.2.1. By Product Type

9.2.4.3.2.2. By Type

9.2.4.3.2.3. By Distribution Channel

10. Middle East & Africa Pain Patch Market Outlook

10.1. Market Size & Forecast

10.1.1. By Value

10.2. Market Share & Forecast

10.2.1. By Product Type

10.2.2. By Type

10.2.3. By

10.2.4. By Distribution Channel

10.2.5. By Country

10.2.5.1. South Africa Pain Patch Market Outlook

10.2.5.1.1. Market Size & Forecast

10.2.5.1.1.1. By Value

10.2.5.1.2. Market Share & Forecast

10.2.5.1.2.1. By Product Type

10.2.5.1.2.2. By Type

10.2.5.1.2.3. By Distribution Channel

10.2.5.2. Saudi Arabia Pain Patch Market Outlook

10.2.5.2.1. Market Size & Forecast

10.2.5.2.1.1. By Value

10.2.5.2.2. Market Share & Forecast

10.2.5.2.2.1. By Product Type

10.2.5.2.2.2. By Type

10.2.5.2.2.3. By Distribution Channel

10.2.5.3. UAE Pain Patch Market Outlook

10.2.5.3.1. Market Size & Forecast

10.2.5.3.1.1. By Value

10.2.5.3.2. Market Share & Forecast

10.2.5.3.2.1. By Product Type

10.2.5.3.2.2. By Type

10.2.5.3.2.3. By Distribution Channel

11. Market Dynamics

11.1. Drivers

11.2. Challenges

12. Market Trends & Developments

12.1. Recent Development

12.2. Mergers & Acquisitions

12.3. Technology Launches

13. Competitive Landscape

13.1. NEXGEL Advanced Hydrogel Solutions

13.1.1. Business Overview

13.1.2. Patient Offerings

13.1.3. Recent Developments

13.1.4. Key Personnel

13.1.5. SWOT Analysis

13.2. Viatris Inc.

13.3. Johnson and Johnson

13.4. Teva Pharmaceutical Industries Ltd.

13.5. Sorrento Therapeutics Inc.

13.6. Hisamitsu Pharmaceutical Co.,Inc.

13.7. Endo International plc.

13.8. Purdue Pharma L.P.

13.9. Amneal Pharmaceuticals LLC

13.10.Grunenthal

14. Strategic Recommendations

15. About us & Disclaimer

Figures and Tables

Frequently asked questions

What was the market size of the Global Pain Patch Market in 2022?

The market size of the Global Pain Patch Market was estimated to be USD 4.95 Billion in 2022.

What is the Study Period for the Global Pain Patch Market?

The Global Pain Patch Market was analyzed for the historical period of 2018 to 2021. While the base year was 2022, estimation for the year 2023 was calculated and the market growth was further forecast for 2024 to 2028.

Who are the top players operating in the Global Pain Patch Market in 2022?

NEXGEL Advanced Hydrogel Solutions, Viatris Inc., Johnson and Johnson, Teva Pharmaceutical Industries Ltd., Sorrento Therapeutics Inc., Hisamitsu Pharmaceutical Co.,Inc., Endo International plc., Purdue Pharma L.P., Amneal Pharmaceuticals LLC, Grunenthal are the top players operating in the Global Pain Patch Market in 2022.