Organ Transplant Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028, Segmented By Product (Tissue Products, Organ Preservation Products, Transplant Diagnostics, Immunosuppressant Drugs, Others), By Application (Organ Transplantation, Tissue Transplantation), By Type of Transplant (Autograft, Allograft, Others), By End User (Hospitals, Transplant Centers, Others), By Region and Competition Forecast

Market Overview

Global Organ Transplant Market has valued at USD 14.56 Billion in 2022 and is anticipated to project robust growth in the forecast period with a CAGR of 8.93% through 2028. The organ transplantation market primarily deals with the procedure of transplanting organs. Organ transplantation is a medical intervention wherein an organ is extracted from one body and implanted into another to address organ failure, fill a void, or replace a damaged or missing organ. This procedure is commonly employed to treat organ failure in vital organs such as the lungs, kidneys, liver, and others. Candidates most commonly considered for organ transplantation are individuals with brain death yet possessing healthy organs that can potentially save another person's life. Prior to undertaking this intricate procedure, obtaining the consent of the patient or their family is of utmost importance, as organ harvesting without consent is deemed an illegal and reprehensible act.

The organ transplant market refers to the sector of the healthcare industry that involves the transplantation of organs and tissues from one individual (donor) to another (recipient) to replace a malfunctioning or damaged organ. Organ transplantation is a complex medical procedure that aims to improve the quality of life and extend the lifespan of individuals with organ failure or certain medical conditions. The market encompasses various aspects related to organ transplantation, including organ procurement, preservation, transplantation surgery, post-operative care, and ongoing management.

Key Market Drivers

Growing Organ Failures and Organ Donations Procedure

The demand for organ transplantation has been on the rise globally in the past decade. This can be attributed to the increased prevalence of vital organ failure, higher success rates of transplantation, and improved post-transplant outcomes. The incidence of organ failure has also increased due to factors such as alcohol consumption, substance abuse, and unhealthy diets leading to chronic diseases affecting vital organs like lungs, kidneys, and liver. Organ transplantations have become a life-saving measure for patients, which is driving the growth of the transplantation market. Furthermore, technological advancements in transplantation methods are contributing to the overall market revenue growth.  The increasing prevalence of chronic diseases leading to organ failures is a significant driver for market growth. The global rise in organ donation has also influenced people to opt for organ transplantation, thereby accelerating market expansion. Furthermore, the excessive consumption of alcohol and unhealthy dietary habits among the population contribute to organ failure, further augmenting market growth. The proliferation of personal insurance, coupled with lifestyle factors contributing to the burden of illness, is projected to bolster market growth. Additionally, the procurement and preservation of organs and tissues are expected to provide further impetus to market expansion.

Increase In the Demand for Organs for Transplant

The global surge in demand for transplant organs can be attributed to the rising incidence of acute diseases, leading to an increase in organ failures. For instance, end-stage renal disease, primarily caused by diabetes and high blood pressure, necessitates kidney transplants or dialysis as the sole treatment options to sustain patient life. As per the U.S. Department of Health & Human Services, approximately 121,678 patients were awaiting organ transplants in the U.S. in 2019. Consequently, there is a substantial demand for advanced transplantation products to address organ failure. To address this challenge, the U.S. government's Health Resources and Services Administration (HRSA) launched an initiative in March 2023 aimed at modernizing the transplantation network and organ procurement. This effort emphasizes the dissemination of new organ donor and transplant data.

Increasing Number of Tissue Banks

Tissue banks have been known to store biomedical tissues under cryogenic conditions. As the demand for tissue transplantation increases, so does the demand for tissue banks that offer a wide range of services including donor assessment, processing, recovery, storage, labeling, and delivery of tissues. These banks primarily rely on low temperature storage to maintain tissues at optimal conditions. The rise in burn injuries has led to a significant demand for tissue banks that specialize in the retrieval and aseptic storage of skin for donation. Moreover, technological advancements such as centrifuges and cryopreservation systems have greatly improved the efficiency of tissue preservation. Furthermore, computerized support systems equipped with advanced hardware and software have made it easier to maintain and manage tissues with high efficiency. These developments have made the storage and retrieval of organs relatively more convenient, thereby driving the growth of the market.

Technological Advancements in Organ Transplant Methods

Technological advancements in the field of 3D bioprinting are playing a significant role in driving the adoption of organ transplantation. The continuous developments in PCR technique, including enhancements in system design and advanced assays, have greatly improved the precision and effectiveness of tissue typing. The pioneering technique known as desensitization, developed by John Hopkins University School of Medicine, has revolutionized kidney transplantation by enabling the use of organs from any donor. Additionally, therapeutic hypothermia, utilizing targeted temperature management, has emerged as a critical factor in organ transplantation, safeguarding neurological functions in patients with cardiac arrest, asphyxia, and stroke. The introduction of these advanced techniques has contributed to the growth of the global transplantation market, leading to an increase in the number of organ transplant procedures worldwide

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Key Market Challenges

Transplant Rejection

Transplant rejection is a complex process whereby the recipient's immune system mounts an attack against the transplanted organ or tissue, recognizing it as foreign. Three types of rejections are commonly observed: hyper-acute rejection, acute rejection, and chronic rejection. Despite meticulous donor matching, tissue typing, and the use of immunosuppressive medications, instances of transplant rejection still occur, leading to organ failure. Non-compliance with immunosuppressive drugs remains a significant contributing factor to rejection. Complications that may arise from transplant rejection include certain types of cancers, infections, impaired function of the transplanted tissue or organ, and adverse effects due to incorrect medication dosages. According to the Organ Procurement and Transplantation Network, approximately 4% of deceased donor kidney transplants experience failure within one year, while living donor kidney transplant recipients face a 14% failure rate at five years post-transplant. Consequently, these factors pose challenges to the growth of the market.

Shortage of Organ Donors

According to the Living Kidney Donors Network, the global number of kidney transplant recipients exceeded 90,000 in 2017, and this figure is projected to rise in the near future. Traditionally, organs are procured from deceased patients who have experienced brain injury or stroke. However, the prevalence of smoking, alcohol consumption, and drug abuse has led to a decline in the pool of healthy individuals suitable for organ donation. Consequently, there is an escalating number of patients on transplant waiting lists, as the availability of suitable organs for transplantation remains limited. Additionally, the lack of awareness surrounding organ donation has emerged as a significant factor impeding market growth. Furthermore, ethical and cultural considerations pose substantial challenges in the transplantation market. Developing and underdeveloped nations often exhibit a lack of awareness regarding organ donation, contributing to hesitance among potential organ donors. Cultural and social stigmas, as well as religious and customary beliefs, frequently discourage organ donation among families. These factors collectively hinder the market's growth prospects.

Key Market Trends

Advances In the Technology and Development

Advances in technology and development have the potential to significantly boost the demand for organ transplants in the future by addressing some of the challenges and limitations currently faced by the field. Progress in technology and advancements in the medical field have facilitated the transplantation of vital organs like the heart, kidney, liver, lungs, and various other organs. Key technical achievements encompass the development of vascular anastomosis techniques, effective management of the immune response through chemical immunosuppressants, and the formulation of preservation solutions.

These advancements can improve organ availability, enhance transplant success rates, and expand the possibilities for transplantation. Technology has the potential to improve organ preservation and transportation methods, enabling organs to remain viable for longer periods before transplantation. This can lead to more efficient organ allocation, reduced wastage, and broader access to viable organs. Advances in bioprinting and tissue engineering are enabling the creation of bioengineered organs and tissues in the laboratory. This technology has the potential to address organ shortages by producing organs on demand, reducing the dependency on donor organs. Developments in immunosuppressive medications can lead to more targeted and effective treatments that minimize the risk of organ rejection. Improved immunosuppressive protocols can increase the success rate of transplant surgeries and reduce the need for high doses of medication. Research into xenotransplantation, the transplantation of organs from animals to humans, holds the potential to overcome the shortage of human donor organs. Advances in genetic editing and immunomodulation are making xenotransplantation more feasible and safer.

Advancements in Regenerative Medicine

Regenerative therapies and tissue engineering are likely to revolutionize organ transplantation by providing alternatives to traditional donor organs. The development of bioengineered tissues, organoids, and lab-grown organs could increase the availability of transplantable tissues.  Scientists are working on creating functional tissues in the laboratory using a combination of cells, scaffolds, and growth factors. These bioengineered tissues could be used to repair damaged organs, restore function, or provide temporary support while waiting for a suitable donor organ. Organoids are miniature, simplified versions of organs grown in the lab from stem cells. They closely mimic the structure and function of actual organs, making them valuable for studying diseases, testing drug responses, and potentially serving as transplantable tissues in the future. Bioengineered tissues and organs can potentially be created using a patient's own cells, reducing the risk of rejection and the need for immunosuppressive medications.

Segmental Insights

Application Insights

The global organ transplant market is categorized into organ transplantation and tissue transplantation, based on application. The organ transplant segment recorded the highest revenue share in 2022. This can be attributed to the increasing demand for organ transplantation worldwide, driven by a rise in cases of organ failure resulting from heavy alcohol consumption and an unhealthy lifestyle. Moreover, continuous technological advancements by key players and healthcare professionals have improved the success rate and post-transplant prognosis, thereby fuelling the revenue growth of this segment. On the other hand, the tissue transplant segment is expected to exhibit a steady growth rate during the forecast period. There is a significant demand for transplants of cornea, bones, skin, nerves, tendons, veins, and heart valves, especially for individuals affected by burns and accidents.

End User Insights

Based on end-user, the global transplantation market is categorized into hospitals, transplant centers, and other facilities. The hospital segment accounted for the largest share of revenue in 2021, primarily due to the increasing number of medical procedures and operations performed in hospitals. Most hospitals have convenient access to well-defined organ databases, which facilitates the verification of organ supply and enables prompt medical interventions. This factor contributes to the revenue growth of the hospital segment. The transplant centers segment is expected to exhibit a stable revenue growth rate during the forecast period. This can be attributed to the growing demand for advanced healthcare centers to meet the increasing need for transplantation procedures. Transplant centers are particularly suitable for older adults as they provide personalized care and minimize the need for frequent visits to hospitals. Moreover, receiving treatment in transplant centers helps reduce the risk of hospital-acquired infections.

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Regional Insights

Based on regional analysis, the transplantation market in North America accounted for the largest share of revenue in 2022. The market's growth in this region is driven by continuous development of innovative transplantation products, a well-developed healthcare system, and increased personal health expenditure by the population. Additionally, the strong presence of various large-scale biotechnology and medical device companies is expected to further drive revenue growth in North America. Moreover, supportive government policies in Canada and the US contribute to the market's growth in this region. The market in the Asia Pacific region is projected to experience a faster revenue growth rate during the forecast period. The increasing prevalence of chronic diseases and the rise in road accidents leading to permanent organ damage are major factors driving revenue growth in this region. Furthermore, continuous advancements in transplantation technology by major players in countries within this region contribute to the revenue growth of the Asia Pacific transplantation market. Meanwhile, the European market is expected to maintain a steady high revenue growth rate during the forecast period. The increasing consumption of drugs and alcohol resulting in organ damage, combined with the strong presence of major market players and availability of skilled doctors, are driving the revenue growth of the market in the region.

Recent Developments

• In February 2022, Amnio Technology introduced two new membrane products: the PalinGen Dual-Layer Membrane and the Dual Layer PalinGen X-Membrane. These novel allografts, like the entire PalinGen membrane product line, undergo minimal manipulation, are intended for homologous use, and are chorion-free.
• In February 2022, Orthofix Medical unveiled Opus BA, a synthetic bioactive bone graft solution designed for cervical and lumbar spine fusion procedures. Opus BA can effectively fill bone voids or gaps within the skeletal system.
• In September 2021, Kidney Transplant Collaborative (KTC) was established as a national nonprofit organization headquartered in Washington, DC. KTC is dedicated to enhancing kidney transplants while addressing financial barriers and other challenges faced by recipients and donors throughout the transplant process.

Key Market Players

• Abbvie, Inc.
• Arthrex, Inc.
• Zimmer Biomet
• Medtronic plc
• Novartis AG
• Stryker Corporation
• 21st Century Medicine
• BiolifeSolutions, Inc.
• Teva Pharmaceuticals
• Veloxis Pharmaceutical

Report Scope:

In this report, the Global Organ Transplant Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

            ·         Organ Transplant Market, By Product:

o   Tissue Products

o   Organ Preservation Products

o   Transplant Diagnostics

o   Immunosuppressant Drugs

o   Others

·         Organ Transplant Market, By Application:

o   Organ Transplantation

o   Tissue Transplantation

            ·         Organ Transplant Market, By Type of Transplant:

o   Autograft

o   Allograft

o   Others

            ·         Organ Transplant Market, By End User:

o   Hospitals

o   Transplant Centers

o   Others

            ·         Organ Transplant Market, By Region:

o   North America

§  United States

§  Canada

§  Mexico

o   Europe

§  France

§  United Kingdom

§  Italy

§  Germany

§  Spain

o   Asia-Pacific

§  China

§  India

§  Japan

§  Australia

§  South Korea

o   South America

§  Brazil

§  Argentina

§  Colombia

o   Middle East & Africa

§  South Africa

§  Saudi Arabia

§  UAE

§  Kuwait

§  Turkey

§  Egypt

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Organ Transplant Market.

Available Customizations:

Global Organ Transplant market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).

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