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Forecast Period
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2024-2028
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Market Size (2022)
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USD 4.03 Billion
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CAGR (2023-2028)
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13.04%
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Fastest Growing Segment
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Cancer Research
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Largest Market
|
North America
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Market Overview
Global Cell Isolation Market has valued
at USD 4.03 Billion in 2022 and is anticipated to project impressive growth in
the forecast period with a CAGR of 13.04% through 2028. Cell isolation, also
known as cell isolation, refers to the process of identifying and removing
specific cells from a heterogeneous mixture of cell population. These targeted
cells are identified, isolated, and separated based on their cell type. Some
commonly utilized methods for cell isolation include magnet-activated cell
isolation, filtration, centrifugation, and flow cytometry. Cell isolation plays
a vital role in diagnosing diseases, conducting cellular research, and
developing therapies by analyzing ribonucleic acid (RNA) expressions. It helps
simplify the experimental analysis of cells and reduces interference from other
cell types within the sample. Consequently, it has extensive applications in
cancer research, stem cell biology, immunology, and neurology. An example of an
innovative technique that utilizes isolated cells is patch-clamp
electrophysiology, which examines the movement of energized particles across
the cell membrane. Isolated cells are also instrumental in cell culture, where
a single cell multiplies to form a colony of cells. Moreover, cell isolation
can be employed in various treatments. For instance, the isolation of pancreatic
islet cells, followed by their culture and transplantation, has been performed
to treat patients with Type 1 Diabetes.
Key Market Drivers
Increasing
Prevalence of Chronic Diseases
The growing incidence of chronic
diseases, such as diabetes and cancer, has led to an increased demand for
cell-based therapies. Additionally, cell isolation plays a crucial role in
various diagnostic experiments and research on chronic diseases. In drug
discovery, cell isolation is essential for studying cellular behavior, disease
response, and drug impact. Cell isolation tools are increasingly utilized in
drug discovery techniques to develop recombinant protein therapeutics for
treating a wide range of diseases, including cancer, autoimmune disorders, and
genetic conditions. The global prevalence of chronic diseases has further
amplified the applications of isolated human cells in research, drug
development, and clinical trials. Therefore, the rising demand for cell-based
therapies, driven by the growing incidence of chronic diseases, has resulted in
an increased need for cell isolation tools.
The growth of chronic diseases, such as
diabetes, obesity, arthritis, heart disorders, and cancer, is influenced by
factors like increased sedentary lifestyle, global population aging, and higher
rates of cigarette smoking and alcohol consumption. According to Imperial
College London, chronic illnesses were projected to account for over 70% of
global fatalities in 2020, with more than 41 million deaths annually.
Approximately 17 million of these deaths are considered premature, occurring at
a younger age than expected.
Consequently, the demand for cellular
therapies to address chronic diseases is escalating alongside the burden of
these conditions. This has led to increased focus and funding in research to
develop effective remedies. As a result, the global market for cell isolation
technologies is being driven by the growing activities in cellular research.
Rapid
Increase in The Research Activities In The Pharmaceutical And Biotechnological
Industries
The robust growth of the Cell Isolation/Cell
isolation Market can be attributed to the significant increase in research
activities within the pharmaceutical and biotechnological industries. This
surge is in response to the rapid rise in the number of diseases, as well as
the presence of well-developed infrastructures and advancements in technology.
These factors contribute to the need for effective cell isolation and
separation techniques, which further drives the market growth.
Moreover, the growing demand for
laboratory automation has also played a pivotal role in enhancing the growth of
the Cell Isolation/Cell isolation Market. As laboratories seek to streamline
their processes and improve efficiency, the adoption of automated solutions for
cell isolation and separation becomes increasingly important. This, in turn,
fuels the expansion of the market, as more companies and research institutions
recognize the benefits and advantages of laboratory automation in their
scientific endeavors. Numerous biotechnology companies, including those from
underdeveloped nations, are venturing into the market. Pharmaceutical
corporations are likely to utilize cell isolation techniques to develop new
medications and foster innovation. These companies have acquired significant
independent units to support the expanding stem cell research field. The
biotechnology and pharmaceutical firms' sector is expected to be propelled by
the advancements in medications and treatments, such as CAR-T, facilitated by cell
isolation technologies. Currently, there are 449 public biotech companies
operating in the U.S., which is anticipated to drive the market for
biotechnology and pharmaceutical companies.
Government’s
Policies to Enhance Biomedical Research Activities
In recent years, there has been a
remarkable surge in initiatives and policies implemented by governments
worldwide to support and promote biomedical research activities. This is
primarily driven by the increasing awareness among customers about the significance
of such research, as well as the growing number of aging population and the
rising prevalence of chronic diseases. Consequently, the Cell Isolation Market
has experienced a rapid growth trajectory.
Substantial investments in the
biotechnology sector and continuous improvements in the healthcare
infrastructure are expected to further stimulate the expansion of the Cell
Isolation Market. These investments and advancements not only contribute to the
overall growth of the market but also foster innovation and technological
advancements in the field of cell isolation and separation.
Demand
For Clinical Trials and Research Is Increasing As The Geriatric Population
Grows
The senior population, comprising
individuals aged 65 and over, is more prone to chronic illnesses such as cancer
and neurological disorders when compared to the younger population. Notably,
the geriatric population is experiencing rapid growth, which further magnifies
the significance of addressing these health concerns. With the increasing
number of individuals aged 65 and over, the prevalence of conditions like
Alzheimer's, dementia, cancer, and immunological illnesses is expected to rise
significantly.
Consequently, there will be an
escalating demand for corrective treatments to cater to these conditions. This
surge in demand is also projected to extend to the field of cell isolation
products, which play a crucial role in various research endeavors, including
clinical trials. As a result, the global market for cell isolation technologies
is anticipated to witness substantial growth, driven by these factors.
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Key Market Challenges
Lack
of Technically Skilled Individuals
The shortage of technically competent
workers in the field, coupled with the increasing concerns about the existence
of tight rules and compliances for cell separation procedures, are projected to
restrain the overall market expansion. Moreover, the high cost associated with
cell separation technology implant treatments can potentially pose a
significant threat to the growth of the market in the coming years. These
factors highlight the need for strategic measures and innovative solutions to
overcome these challenges and foster sustainable market growth.
Shift
From Lab-Based Diagnosis to Home-Based Testing
The shift from lab-based diagnosis to
home-based testing, driven by increased customer awareness, has led to a
decrease in the chances of complications and significant advancements in
technology. As a result, the growth of the Cell Isolation/Cell Separation
Market is anticipated to be reduced. Additionally, the market growth may be
hampered by the high costs associated with service contracts and raw materials.
These factors collectively contribute to the challenges faced by the Cell
Isolation Market, emphasizing the need for strategic solutions to address these
concerns and ensure sustained growth in the industry.
Key Market Trends
Technological
Advancement
It is anticipated that the cell
separation technology market will experience significant growth opportunities
in the coming years. This can be attributed to the rapid technological
advancements in cell-based technology, such as higher purity yield and reduced cell
isolation time. Additionally, the rise in government initiatives to improve
cell-based technology and the cost-effectiveness of cell separation techniques
are expected to contribute to market growth. Furthermore, the well-developed
healthcare infrastructure in developing countries provides a favorable
environment for the adoption and implementation of cell separation
technologies. All these factors combined make the cell separation technology
market poised for substantial expansion in the foreseeable future.
Product
Innovations
The growth of the global cell isolation
market is being fueled by advancements in the product offerings. Product
innovations in this market are primarily driven by the increasing demand for
automated tools in cell-based research for various chronic and infectious
diseases. Key players in the market, such as BD and QIAGEN, are dedicated to
continuous product improvement. For instance, in March 2019, BD introduced the
BD FACSDuet automated flow cytometry system, a fully automated sample
preparation instrument that enhances the efficiency of clinical laboratories by
minimizing errors and reducing the need for manual user interactions when
running assays on the BD FACSLyric clinical flow cytometer. Other vendors, like
Bio-Rad, are focused on the development of reagents for flow cytometry. In
November 2020, Bio-Rad Laboratories, Inc. launched StarBright Blue 700,
StarBright Violet 440, and StarBright Violet 610 dyes, which provide maximum
brightness and improved resolution for flow cytometry. Hence, the continuous
product advancements by established market players drive market growth and
contribute to increased sales of these products.
Segmental Insights
Cell Type Insights
Based on the cell type, the market is segmented into human cells
and animal cells. In 2022, the human cell category emerged as the leader in
terms of revenue share. This can be attributed to the growing emphasis on
cancer and human research, as well as the wide range of applications of
isolated human cells in biopharmaceutical development, clinical trials, and
research. Moreover, the attractive payment policies for personalized medicine
in industrialized countries further contribute to the demand for human cell
isolation. It is projected that the animal cells segment will also witness
profitable growth during the forecast period. The development of novel drugs
has garnered significant attention from government bodies, the commercial
sector, and healthcare organizations, thereby driving the growth of this
segment. Animal cells play a crucial role in the discovery and development of
new drugs, enabling the assessment of toxicity, pharmacokinetics, and
effectiveness.
Technique Insights
Based on
the technique segment, the market is segmented into centrifugation-based cell
isolation, surface marker-based cell isolation, and filtration-based cell
isolation. The centrifugation-based cell isolation segment, accounted for the
largest revenue share in 2022, has been a dominant force in the cell separation
market. This technique is widely utilized by academic institutions, research
centers, and biotechnology/biopharmaceutical companies. Centrifugation plays a
crucial role in cell isolation, with both differential centrifugation and
density gradient centrifugation commonly employed. Density gradient
centrifugation leverages molecular weights for particle separation, while
differential centrifugation employs lysates to disrupt cell membranes.
Looking
ahead, significant growth is expected in both the surface marking and
filtration segments. This market expansion is primarily driven by product
development and increased corporate investments in manufacturing
infrastructure. Manufacturers utilize innovative surface markers and filtration
systems in their production and research processes to enhance the quality of
the final product.
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Regional Insights
The North
American market is poised to lead the global cell isolation industry in the
coming years, driven by the increasing prevalence of chronic diseases, growing
demand for personalized medicine, and government funding for cell-based
research and development. With its advanced healthcare system, robust research
and development sector, and increasing investment in biotechnology research,
North America is expected to witness the most significant revenue growth.
Asia
Pacific is anticipated to experience rapid expansion in the cell isolation
market due to factors such as escalating healthcare costs, a large patient
base, and growing interest in cutting-edge cell separation methods. The region
boasts several emerging nations, including China and India, where the incidence
of chronic diseases is on the rise. Additionally, the accessibility to skilled
personnel and affordable production costs is expected to attract numerous major
players in the cell isolation industry to the region.
The
European market is projected to exhibit moderate growth, driven by factors such
as increased government spending on life sciences research and development and
the prevalence of chronic disorders. Key players in the cell isolation market,
such as Thermo Fisher Scientific, STEMCELL Technologies, and Merck KGaA, are
among the notable companies based in the region.
Recent Developments
In October
2022, Thermo Fisher Scientific introduced a closed and automated cell isolation
and bead removal solution to enhance the evolution of cell therapy
manufacturing. This novel technology enhances cell purity and isolation
efficiency, while also increasing the recovery of target cells for scalable
cell therapy production.
In January
2022, Sony Corporation launched CGX10, an advanced cell isolation system that
efficiently sorts cells at high speed and purity within a closed system.
In April 2019, Becton, Dickinson and Company (BD) released BD
BACTEC platelet quality control media, enabling microbiology laboratories,
blood banks, and transfusion services to identify contaminated platelet units.
Key Market Players
- Becton, Dickinson & Company
- Merck KGaA (Millipore Sigma)
- Thermo Fisher Scientific Inc.
- Bio-Rad Laboratories Inc.
- Terumo Corporation
- PluriSelect Life Science UG & Co. KG
- Danaher Corporation (Cytiva)
- STEMCELL Technologies Inc.
- Corning Inc.
- Akadeum Life Sciences Inc.
|
By Product
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By Cell Type
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By Source
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By Technique
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By Application
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By End User
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By Region
|
|
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Consumables
Instruments
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Human Cells
Animal Cells
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Bone Marrow
Cord Blood/Embryonic
Stem Cells
Adipose Tissue
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Centrifugation-Based
Cell Isolation
Surface Marker-Based
Cell Isolation
Filtration-Based Cell
Isolation
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Biomolecule Isolation
Cancer Research
Stem Cell Research
In Vitro Diagnostic
Others
|
Biotechnology and
Biopharmaceutical Companies
Research Laboratories
and Institutes
Hospitals and
Diagnostic Laboratories
Cell Banks
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North America
Europe
Asia Pacific
South America
Middle East &
Africa
|
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Report Scope:
In this report, the Global Cell Isolation Market
has been segmented
into the following categories, in addition to the industry trends which have
also been detailed below:
·
Cell Isolation Market, By Product:
o
Consumables
o
Instruments
·
Cell Isolation Market, By Cell Type:
o
Human Cells
o
Animal Cells
·
Cell Isolation Market, By Source:
o
Bone Marrow
o
Cord Blood/Embryonic Stem
Cells
o
Adipose Tissue
·
Cell Isolation Market, By Technique:
o
Centrifugation-Based Cell
Isolation
o
Surface Marker-Based Cell
Isolation
o
Filtration-Based Cell
·
Cell Isolation Market, By Application:
o
Biomolecule Isolation
o
Cancer Research
o
Stem Cell Research
o
In Vitro Diagnostic
o
Others
·
Cell Isolation Market, By End User:
o
Biotechnology and
Biopharmaceutical Companies
o
Research Laboratories and
Institutes
o
Hospitals and Diagnostic
Laboratories
o
Cell Banks
·
Cell Isolation Market, By Region:
o North America
§ United States
§ Canada
§ Mexico
o Europe
§ France
§ United Kingdom
§ Italy
§ Germany
§ Spain
o Asia-Pacific
§ China
§ India
§ Japan
§ Australia
§ South Korea
o South America
§ Brazil
§ Argentina
§ Colombia
o Middle East & Africa
§ South Africa
§ Saudi Arabia
§ UAE
§ Kuwait
§ Turkey
§ Egypt
Competitive Landscape
Company
Profiles: Detailed
analysis of the major companies present in the Global Cell Isolation Market.
Available Customizations:
Global Cell Isolation market report with the given market data,
Tech Sci Research offers customizations according to a company's specific
needs. The following customization options are available for the report:
Company Information
- Detailed analysis and profiling of additional market players (up to
five).
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