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Lumos Diagnostics Limited receives US-FDA Clearance for FebriDx POC Test

Australia: On 3 July 2023, Lumos Diagnostics Limited have announced that they have received approval for FebriDx POC test to identify bacterial acute respiratory infection. The test entails the use of an immunoassay on a finger prick blood specimen to offer concurrent, qualitative assessment of increased amounts of C-reactive protein (CRP) and myxovirus resistance protein A (MxA). FebriDx POC test utilizes an innovative dual biomarker technology to quickly determine whether an infection is caused by a virus or bacteria. The approval permits FebriDx to be marketed in the United States for utilization by medical practitioners as a tool in identifying acute respiratory infection. Moreover, it is intended to be used in conjunction with clinical indications and symptoms, along with other clinical and laboratory discoveries. FebriDx is currently authorized in the UK, Europe, Canada, UAE, Brazil, Turkey, Pakistan, Singapore, Malaysia, and Australia.

The improper and redundant prescribing of antibiotics is acknowledged as a significant contributing factor to the increasing worldwide emergence of antimicrobial resistant (AMR) strains of bacterial pathogens. In 2021, US healthcare professionals practicing in non-hospital settings wrote 211 million antibiotic prescriptions, accounting for 636 prescriptions per 1,000 individuals. Although acute respiratory infections are mostly caused by viruses, they are the most frequent reason for prescribing antibiotics, and around 40% of these prescriptions are considered unnecessary. To conquer this issue Lumos Diagnostics filed a new 510(k) submission for FebriDx POC test to the FDA in earlier 2023. On 3rd July FDA concluded its evaluation and determined that FebriDx test has shown significant similarity to the reference device mentioned in this application.

According to the CEO of Lumos Diagnostics Limited, “We are delighted to finally secure clearance to market our FebriDx rapid, point–of–care test in the US as we continue to believe it has an important role to play in antibiotic stewardship. It is a credit to the Regulatory team at Lumos that we have been able to deliver this outcome from our new 510(k) application significantly ahead of our initial expectations. With this clearance in hand, we anticipate securing our first commercial orders in the US before the end of calendar year 2023. In the meantime, we are continuing to work with distribution partners and potential licensees, as well as establish our own focused sales effort, as we prepare to launch FebriDx in the US.”

According to TechSci Research, The combination of innovative strategies and new product launches have consistently emerged as remarkable approaches to achieve technological advancements in the global healthcare system. Point-of-care testing (POCT) is a rapidly expanding diagnostic tool that offers a swift test outcome for immediate clinical decisions. However, clearance of FebriDx POC test have upgraded the portfolio of Lumos Diagnostics Limited which specializes in rapid and cost-effective point-of-care diagnostic testing technologies. Moreover, the company excels in developing and marketing innovative Lumos-branded POC tests that focus on infectious and inflammatory ailments. The clinical performance of the FebriDx examination has been assessed in two ongoing multicenter clinical trials in the United States. Consequently, the FebriDx test exhibited a notable level of accuracy in diagnosing patients with clinically significant bacterial and viral acute respiratory infections.

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