G-Protein Coupled Receptors Market to Grow with a CAGR of 5.23% through 2030
Increasing
investment in precision medicine and the growing adoption of AI-driven drug
development for GPCR-targeted therapies, is expected to drive the Global G-Protein
Coupled Receptors Market growth in the forecast period, 2026-2030
According to
TechSci Research report, “G-Protein Coupled Receptors Market – Global
Industry Size, Share, Trends, Competition Forecast & Opportunities, 2030F”,
the Global G-Protein Coupled Receptors Market stood at USD 3.95 Billion in
2024 and is expected to reach USD 5.37 Billion by 2030 with a CAGR of 5.23% during
the forecast period. The Global G-Protein Coupled Receptors (GPCR) Market is
experiencing rapid expansion due to its vital role in cellular signaling and
drug development. GPCRs are among the most versatile drug targets, regulating
numerous physiological functions such as immune response, neurotransmission,
and hormone regulation. With pharmaceutical companies focusing on
next-generation therapeutics, GPCR-targeted drugs are gaining traction in
treating diseases like diabetes, psychiatric disorders, and autoimmune
conditions. Advances in structural elucidation techniques, including X-ray
crystallography and nuclear magnetic resonance (NMR) spectroscopy, have
significantly improved the understanding of GPCR mechanisms, fostering drug
discovery. The emergence of selective GPCR modulators and combination therapies
has expanded treatment options, further propelling market growth.
The increasing
demand for innovative treatment options is fueling investments in GPCR-targeted
biologics and peptide-based drugs. The rise of precision pharmacology has
enabled the development of GPCR allosteric modulators, offering better receptor
selectivity and reduced side effects. The adoption of artificial intelligence
(AI) in GPCR modeling has streamlined ligand-binding studies, expediting drug
discovery pipelines. Growing interest in functional selectivity has led to the
identification of biased agonists, allowing for more targeted therapeutic
effects. Expansion in gene-editing technologies such as CRISPR is facilitating
research into GPCR gene regulation, unlocking new possibilities for disease
modification. The integration of lab-on-a-chip technologies for high-throughput
GPCR screening has also enhanced drug testing efficiency, accelerating market
development.
The emergence of
GPCR-targeted therapies in immuno-oncology presents a major growth avenue, with
researchers exploring novel GPCR-mediated pathways for cancer treatment. The
expansion of biosimilar and biologic drugs targeting GPCRs is expected to
create cost-effective treatment alternatives, enhancing patient access.
Increasing research into orphan GPCRs, which currently lack identified ligands,
holds potential for discovering breakthrough therapies. The integration of
nanotechnology in GPCR drug delivery is improving therapeutic precision,
reducing systemic side effects. Partnerships between biotech firms and academic
institutions are fostering innovation, leading to a deeper understanding of
GPCR pharmacology and expanding the range of druggable GPCR targets. With
continued technological advancements and industry
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"Global G-Protein Coupled Receptors Market”
The Global G-Protein
Coupled Receptors Market is segmented into product, assay type, application, regional
distribution, and company.
Based on the Application,
Inflammation Research emerged as the fastest growing segment in the Global G-Protein
Coupled Receptors Market during the forecast period. This is due to the increasing recognition of
GPCRs as key regulators of immune and inflammatory responses. GPCRs play a
crucial role in mediating signal transduction in various inflammatory pathways,
making them attractive targets for drug development. The rising prevalence of
chronic inflammatory diseases, including rheumatoid arthritis, inflammatory
bowel disease, and psoriasis, has driven extensive research into GPCR-targeted
therapies. Pharmaceutical and biotechnology companies are actively investing in
identifying novel GPCR modulators that can help regulate immune responses,
reduce inflammation, and provide more effective treatment options. Recent
advancements in high-throughput screening technologies have facilitated the
identification of GPCR-based drug candidates, accelerating the development of
new anti-inflammatory drugs. The growing demand for biologics and
small-molecule drugs targeting GPCRs in inflammation-related disorders is
further fueling market expansion. Additionally, regulatory approvals for
GPCR-targeted therapies in inflammation management are encouraging further
research and innovation in this domain. The increasing burden of inflammatory
diseases, coupled with continuous advancements in GPCR drug discovery and
development, is expected to drive significant growth in this segment during the
forecast period.
Based
on the Region, Asia-Pacific emerged as the fastest growing region in the Global
G-Protein Coupled Receptors Market during
the forecast period. This is due to increasing investments in drug discovery,
rising healthcare expenditures, and expanding pharmaceutical and biotechnology
industries. The region is experiencing rapid advancements in biomedical
research, supported by government initiatives and funding for innovative drug
development. Countries such as China, Japan, and India are becoming key hubs
for GPCR-targeted research due to the availability of skilled researchers,
improved research infrastructure, and collaborations between academic institutions
and pharmaceutical companies. Pharmaceutical companies are focusing on
developing novel GPCR-based drugs to address the growing disease burden.
Furthermore, the presence of a large patient population and evolving regulatory
frameworks supporting faster drug approvals have encouraged market expansion.
The growth of contract research organizations (CROs) and increased foreign
direct investment in the region are further propelling the adoption of GPCR
research technologies. With continuous advancements in drug discovery,
increasing clinical trials, and a strong pipeline of GPCR-targeted
therapeutics, Asia-Pacific is expected to witness significant market growth
during the forecast period.
Major
companies operating in Global G-Protein Coupled Receptors Market are:
- Thermo
Fisher Scientific Inc.
- PerkinElmer
Inc.
- Promega
Corporation
- Merck
KGaA
- Abcam
plc
- Becton,
Dickinson and Company
- Danaher
Corporation
- QIAGEN
N.V.
- Bio-Techne
Corporation
- WuXi
AppTec
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“The Global G-Protein Coupled Receptors
Market is expanding due to the increasing adoption of advanced drug screening
technologies that enhance the efficiency and accuracy of GPCR-targeted drug
discovery. The integration of artificial intelligence (AI) and machine learning
(ML) in the research and development of GPCR-based therapies is helping to
predict molecular interactions, optimize drug design, and identify novel
therapeutic targets. These technologies enable faster and more cost-effective
discovery processes, increasing the number of GPCR-targeted drug candidates
entering clinical trials. The growing emphasis on AI-driven drug discovery
platforms is driving innovations and accelerating the development of new
GPCR-targeted treatments.,” said Mr. Karan Chechi, Research Director of TechSci
Research, a research-based management consulting firm.
“G-Protein Coupled
Receptors Market - Global Industry Size, Share, Trends, Opportunity, and
Forecast, Segmented By Product (Cell Lines, Detection Kits, Cell Culture
Reagents, Ligands), By Assay Type (cAMP Functional Assays, Calcium Functional
Assays, β-Arrestin Functional Assays, Radioligand Binding & GTPγS
Functional Assays, Internalization Assays, Trafficking Assays, Others), By
Application (Cancer Research, CNS Research, Metabolic Research, Cardiovascular
Research, Respiratory Research, Inflammation Research, Others), By Region and
Competition, 2020-2030F”, has evaluated the future growth potential of Global
G-Protein Coupled Receptors Market and provides statistics & information on
market size, structure and future market growth. The report intends to provide
cutting-edge market intelligence and help decision makers take sound investment
decisions. Besides, the report also identifies and analyzes the emerging trends
along with essential drivers, challenges, and opportunities in Global G-Protein
Coupled Receptors Market.
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