Protein A Resin Market to Grow with a CAGR of 9.91% through 2029
Increasing Investments in Research and Development and
supportive Stringent Regulatory Standard are the drivers for the Global Protein
A Resin Market
According to
TechSci Research report, “Protein A Resin Market – Global Industry Size,
Share, Trends, Competition Forecast & Opportunities, 2029”, the Global Protein A Resin Market
was valued at USD 1.32 billion in 2023 and will see an impressive growth in
the forecast period at a CAGR of 9.91% to 2029. Monoclonal antibodies are among
the fastest-growing segments of the biopharmaceutical industry. They are used
in the treatment of various diseases, including cancer, autoimmune disorders,
and infectious diseases. Protein A Resin is a critical component in the
purification process of mAbs, making it an essential consumable in the
production of these therapeutic agents.
The
biopharmaceutical industry continues to invest heavily in the development of
novel biologics and biosimilars. Biologics, including therapeutic proteins,
enzymes, hormones, and growth factors, offer targeted treatments with fewer
side effects compared to traditional small molecule drugs. Protein A Resin is
used in the purification process of biologics and biosimilars, driving its
demand as the industry expands. Biopharmaceutical companies are investing
significant resources in research and development to discover and develop
innovative therapies for a wide range of diseases. The discovery of novel
therapeutic targets and the advancement of bioprocessing technologies drive the
demand for Protein A Resin, which plays a crucial role in purifying therapeutic
proteins and antibodies during the manufacturing process.
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Protein A Resin production
involves complex manufacturing processes, including ligand immobilization,
resin matrix synthesis, and quality control testing. These processes require
specialized equipment, raw materials, and skilled personnel, contributing to
high production costs for manufacturers. The cost of raw materials, including
agarose beads, ligands, and chemical reagents, represents a significant portion
of the overall production costs for Protein A Resin. Fluctuations in raw
material prices, supply chain disruptions, and geopolitical factors can impact
material costs and contribute to cost pressure in the market. Protein A Resin
manufacturer must adhere to stringent quality control standards and regulatory
requirements to ensure the safety, efficacy, and purity of their products.
Quality control testing, validation studies, and compliance with regulatory
guidelines add to the cost of production and may require substantial
investments in infrastructure, equipment, and personnel. The Protein A Resin Market
is highly competitive, with multiple suppliers vying for market share. Intense
competition among manufacturers and suppliers may lead to pricing pressure and
margin erosion, particularly in mature market segments where price becomes a
key differentiator.
The Global Protein
A Resin Market is segmented into Product, Matrix Type, Application, End User, regional
distribution, and company
Based on its Application,
Global Protein A Resin Market is segmented into Immunoprecipitation (IP),
Antibody Purification. Immunoprecipitation (IP) is a technique used to isolate and purify
specific proteins or protein complexes from a complex mixture, such as cell
lysates or tissue extracts, based on the interaction between an antibody and
its target antigen. Protein A Resin can be used as a support matrix in
immunoprecipitation assays to facilitate the isolation and purification of
antibody-antigen complexes. Protein A is a bacterial protein that exhibits high
affinity and specificity for the Fc region of immunoglobulin G (IgG) antibodies
from various species, including humans, mice, and rats. Protein A Resin
consists of Protein A ligands immobilized onto a solid support matrix, such as
agarose beads or magnetic particles. The sample containing the target protein
or protein complex of interest is incubated with Protein A Resin conjugated to
antibodies specific to the target antigen. During this incubation step, the
antibodies present in the sample bind specifically to their target antigens,
forming antibody-antigen complexes.
Based on region,
North America is dominating the market.
North American biopharmaceutical companies often engage in
strategic partnerships, collaborations, and alliances with academic
institutions, contract manufacturing organizations (CMOs), and technology
providers to leverage expertise, access cutting-edge technologies, and optimize
bioprocessing workflows. These collaborations drive innovation and contribute
to the development and commercialization of advanced protein A resin products
and purification technologies. North America has been at the forefront of
adopting biosimilars and biologics for the treatment of various diseases,
including cancer, autoimmune disorders, and infectious diseases. The increasing
demand for biosimilars and biologics, particularly monoclonal antibodies,
drives the demand for protein A resin in the region, further consolidating
North America's position as a dominant player in the global protein A resin
market.
Major companies
operating in Global Protein A Resin Market are:
- GE Healthcare
- Merck Millipore
- PerkinElmer, Inc.
- GenScript Biotech Corp.
- Agilent Technologies
- Repligen Corp.
- Thermo Fisher Scientific Inc.
- Bio-Rad Laboratories, Inc.
- Abcam PLC.
- Novasep Holdings SAS
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“The Protein A
Resin Market is poised for sustained growth and innovation fueled by
advancements in bioprocessing technologies, rising demand for biologics and
biosimilars, and expanding applications in personalized medicine and precision
healthcare. To thrive in this dynamic industry landscape, industry players must
remain attuned to emerging trends, tackle sector-specific challenges, and
capitalize on collaboration and innovation opportunities. Doing so will enable
players in the Protein A Resin Market to position themselves strategically for
success amid the evolving biopharmaceutical sector.,” said Mr. Karan Chechi,
Research Director with TechSci Research, a research-based management consulting
firm.
“Protein A Resin Market - Global Industry Size,
Share, Trends, Opportunity, and Forecast, 2019-2029 Segmented By Product (Natural Protein
A, Recombinant Protein A), By Matrix Type (Agarose-based, Glass or Silica
Based, Organic Polymer Based), By Application (Immunoprecipitation (IP),
Antibody Purification), By End User (Biopharmaceutical Manufacturers, Clinical
Research Laboratories, Academic Institutes), By Region, and By Competition”, has evaluated
the future growth potential of Global Protein A Resin Market and provides
statistics & information on market size, structure and future market
growth. The report intends to provide cutting-edge market intelligence and help
decision makers take sound investment decisions. Besides, the report also
identifies and analyzes the emerging trends along with essential drivers,
challenges, and opportunities in Global Protein A Resin Market.
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