Press Release

Critical Limb Ischemia Treatment Market to Grow with a CAGR of 7.25% through 2028

Rising prevalence of diabetes brought on by an aging global population is expected to drive the Global Critical Limb Ischemia Treatment Market growth in the forecast period, 2024-2028.


According to TechSci Research report, “Critical Limb Ischemia Treatment Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028”, the Global Critical Limb Ischemia Treatment Market stood at USD 3.86 Billion in 2022 and is anticipated to project robust growth in the forecast period with a CAGR of 7.25% through 2028. The market for critical limb ischemia will rise due to the rising prevalence of diabetes brought on by an aging global population and improved critical limb ischemia treatment options. In addition, despite the disease's complexity and low visibility, businesses are actively working to produce critical limb ischemia medications to meet the unmet needs of the condition. The condition is not properly identified or treated, increasing morbidity, mortality, and expenses. A lack of knowledge and other diseases with a similar presentation hampers the expansion of the critical limb ischemia market. Along with the failure of medications in clinical development, the evolution of the critical limb ischemia market is also constrained by rigorous pricing and reimbursement regulations. Furthermore, the accessibility of surgical techniques can make it challenging for novel treatments to gain traction.


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The lack of comprehensive knowledge regarding the epidemiology and etiology of the disease has declined the development of successful therapy options. Leading market participants for the treatment of critical limb ischemia consequently reported a reduction in revenue due to the pandemic. The market has been bouncing back from COVID-19, nevertheless, due to the relaxation of regulations by governments worldwide. During the forecast period, the devices segment is anticipated to hold a significant share of the worldwide critical limb ischemia therapy market. Stents and dilation devices successfully dilate the artery while safeguarding the arterial wall. These are the tools that are frequently used to treat critical limb ischemia. Patients experience a higher quality of life thanks to the low complication rates and the tremendous technical success of dilation devices and stents. During the forecast period, the devices segment is expected to be driven by these benefits. The growing number of FDA approvals and patient preference for revascularization as the first line of treatment can also be attributed to the segment's dominance.


The Global Critical Limb Ischemia Treatment Market is segmented into Treatment, and company.


Based on the Devices, the Embolic Protection Devices segment is anticipated to witness substantial market growth throughout the forecast period. The Global Critical Limb Ischemia (CLI) Treatment Market is experiencing substantial growth propelled by the widespread adoption of Embolic Protection Devices (EPDs). These specialized devices play a pivotal role in enhancing the safety and efficacy of endovascular interventions for critical limb ischemia by preventing the migration of embolic debris during procedures. Embolic events, where debris breaks loose and travels downstream, can exacerbate vascular complications in CLI patients. EPDs act as a safeguard, capturing and removing embolic material, thus minimizing the risk of distal embolization and subsequent tissue damage.


Based on the Drugs segment, the Antihypertensive Agents segment has been the dominant force in the market. The Global Critical Limb Ischemia (CLI) Treatment Market is experiencing growth driven by the integral role of Antihypertensive Agents in managing vascular health. Antihypertensive medications, designed to lower blood pressure, play a crucial role in preventing and managing conditions associated with critical limb ischemia. Hypertension is a significant risk factor for vascular diseases, and controlling blood pressure is paramount in preventing further deterioration of peripheral arteries. As physicians increasingly recognize the importance of managing cardiovascular risk factors in CLI patients, antihypertensive agents have become cornerstone components of comprehensive treatment strategies. These medications not only contribute to blood pressure control but also help mitigate the progression of atherosclerosis, a common underlying cause of critical limb ischemia.


Major companies operating in Global Critical Limb Ischemia Treatment Market are:

  • Medtronic Plc
  • LimFlow SA
  • Cynata Therapeutics Ltd
  • Cardiovascular Systems, Inc.
  • Eli Lilly and Company
  • Abbott Laboratories
  • Rexgenero Ltd.
  • Cesca Therapeutics (ThermoGenesis Holdings, Inc)
  • Teva Pharmaceuticals
  • Micro Medical Solutions
  • Boston Scientific Corporation


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“Additionally, the growing prevalence of the risk factors which increase CLI incidence is expected to boost the growth of the market. Various strategies adopted by the market players such as product launches, mergers and acquisitions, and product development are expected to support the market's expansion over the forecast period. The rising company activities for developing bone graft substitute products and the rising adoption of various business strategies such as collaborations, mergers, and acquisitions are all anticipated to increase the market growth over the forecast period. The increasing focus of the company to develop technologically advanced devices and drugs to treat critical limb ischemia is expected to augment the growth of the market.” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based management consulting firm.


Critical Limb Ischemia Treatment Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented By Treatment (Drugs, Devices), By Drugs (Antiplatelet Drugs, Antihypertensive Agents, Lipid-lowering Agents, Antithrombotic Agents, Others), By Devices (Embolic Protection Devices, Peripheral Dilatation System, Balloon Dilators, Vascular Stents), By Region, By Competition”, has evaluated the future growth potential of Global Critical Limb Ischemia Treatment Market and provides statistics & information on market size, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Critical Limb Ischemia Treatment Market.


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