Press Release

Pediatric Clinical Trials Market to grow with a CAGR of 7.50%

Increasing healthcare infrastructure and a supportive regulatory environment are the major drivers for the Global Pediatric Clinical Trials Market.

 

According to TechSci Research report, “Global Pediatric Clinical Trials Market Industry Size, Share, Trends, Competition, Opportunity and Forecast, 2018-2028”, Global Pediatric Clinical Trials Market has valued at USD 14.70 billion in 2022 and is anticipated to witness an impressive growth in the forecast period with a CAGR of 7.50% through 2028. This can be due to collaborations and partnerships among leading companies with a diverse approach to merge the expertise of individual companies and to strengthen their position in the market.

The globalization of clinical trials is a driver for the global pediatric clinical trials market. The globalization of clinical trials refers to the practice of conducting clinical research in multiple countries or regions outside the sponsor's home country. Conducting clinical trials on a global scale allows researchers to access diverse patient populations, including children from different ethnic backgrounds and geographic regions. This diversity is crucial for understanding how treatments may vary across populations and for generalizing trial results. Globalization increases the pool of potential pediatric participants, which is particularly important for rare diseases or conditions that affect only a small number of children in any single region. A larger participant pool can expedite patient recruitment. Enrolling participants in pediatric clinical trials can be challenging due to the limited number of eligible patients at a single site or country. Globalization can help accelerate recruitment and reduce the time required to complete trials. Conducting trials in different countries or regions allows researchers to observe how treatments perform in various healthcare settings, including academic medical centers, community hospitals, and clinics. This diversity enhances the generalizability of trial results.

 

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Children are a unique demographic with significant physiological and developmental differences from adults. Clinical trials in children are essential to develop age-specific, empirically validated drugs and therapies as well as to determine and improve the best medical care currently available. Clinical studies involving children are essential because they help identify the best pediatric preventative measures. Children go through a variety of physiological processes as they develop from infancy through adolescence and adulthood. They are not merely little adults. As a result of the differences in how children's bodies function from adults', pediatric-specific drugs and preventatives must be developed rather than just modifying adult dosages and therapies for children.

In July 2022, A Phase 3 trial evaluating the investigational use of Dupixent (dupilumab) in children aged 1 to 11 years with eosinophilic esophagitis (EoE) met its primary endpoint of histological disease remission at 16 weeks with both higher and lower dose weight-tiered regimens, according to a press release from Regeneron Pharmaceuticals, Inc., and Sanofi. For kids under the age of 12, there are no recognized treatments for EoE. EoE is a chronic inflammatory condition that harms the oesophagus and impairs its functionality. Dupixent's effects on adults and kids with EoE show that IL-4 and IL-13 are important regulators of the type 2 inflammation that underlies this condition. Children with eosinophilic esophagitis frequently have acid reflux, vomiting, stomach pain, difficulty swallowing, and failure to thrive. These symptoms may have an adverse effect on growth and development as well as lead to a dread of food that may last into adulthood.

The lack of pediatric expertise is a significant challenge in the global pediatric clinical trials market. This challenge manifests in several ways and can impact the planning, execution, and success of pediatric clinical trials. Pediatric clinical trials require specialized knowledge of pediatric medicine, including the unique physiological and developmental differences in children compared to adults. Lack of expertise in pediatric healthcare can lead to difficulties in designing appropriate trial protocols and understanding the specific needs of pediatric participants. Determining appropriate dosing regimens for pediatric patients is complex due to age-related variations in drug metabolism, body weight, and developmental stages. Pediatric experts are crucial for calculating and adjusting dosages to ensure safety and efficacy. Pediatric trials must have expertise in managing adverse events and side effects that may be unique to children. Understanding the signs, symptoms, and appropriate interventions for pediatric adverse events is essential.

Global Pediatric Clinical Trials Market segmentation is based on phase, study design, therapeutic area, region and company

Based on study design, Global Pediatric Clinical Trials Market is segmented into Treatment Studies and Observational Studies. Observational studies in pediatric clinical trials are research investigations in which researchers observe and collect data from pediatric patients without intervening or administering specific treatments. These studies are designed to gain insights into various aspects of pediatric health, disease, and treatment outcomes by observing patients in their natural clinical settings. The primary objective of observational studies is to gather real-world data on pediatric patients' characteristics, behaviors, treatments, or outcomes over time. These studies aim to understand patterns, associations, and trends within the observed population. Unlike interventional clinical trials, observational studies do not involve administering experimental treatments or interventions to participants. Instead, researchers observe and document what occurs naturally during routine clinical care.

Based on Region, North America dominated the Global Pediatric Clinical Trials Market. The United States invests heavily in research and development (R&D), which includes funding for pediatric clinical trials. Government agencies, private foundations, and industry players contribute to this funding. North America represents a lucrative market for pediatric drugs due to its large population and high healthcare spending. This market attractiveness incentivizes pharmaceutical companies to invest in pediatric clinical trials to gain regulatory approvals. The region has made significant advancements in pediatric medicine and research, which further strengthens its position in the global pediatric clinical trials market.

Asia-pacific region to fastest growth in the Global Pediatric Clinical Trials Market. The Asia-Pacific region has a substantial pediatric population, including infants, children, and adolescents. This large and diverse population provides a significant pool of potential participants for pediatric clinical trials. The prevalence of pediatric diseases and health issues is rising in the Asia-Pacific region. Factors such as changing lifestyles, environmental factors, and infectious diseases contribute to a growing pediatric healthcare burden. This trend drives the demand for clinical research and innovative treatments. Many pharmaceutical companies and clinical research organizations recognize the market potential in the Asia-Pacific region, particularly for pediatric drug development. The region's growth presents an opportunity to develop and market pediatric medications and therapies.

 

Some of the major companies operating in the Global Pediatric Clinical Trials Market include:

  • Bristol-Myers Squibb Company
  • Charles River Laboratories International Inc.
  • Covance Inc.
  • GlaxoSmithKline plc
  • ICON plc
  • IQVIA Inc.
  • Novartis AG
  • Pfizer, Inc.
  • Pharmaceutical Product Development, LLC
  • Syneos Health Inc.    
  • Paidion Research, Inc.
  • The Emmes Company, LLC

 

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“Certain areas, particularly in North America, are projected to exert significant demand of drugs. The growth in the competitive landscape and the presence of well-established companies in the market, committed to enhance the overall wellbeing of people each year, are expected to contribute to a remarkable growth of the Global Pediatric Clinical Trials Market in the forecast period," said Mr. Karan Chechi, Research Director with TechSci Research, a research-based Global management consulting firm.

Pediatric Clinical Trials Market – Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented by Phase (Phase I, Phase II, Phase III, and Phase IV), Study Design (Treatment Studies and Observational Studies), Therapeutic Area (Respiratory Diseases, Infectious Diseases, Oncology, Diabetes, and Other Therapeutic Areas), and By Region, Competition evaluated the future growth potential of Global Pediatric Clinical Trials Market and provides statistics & information on market size, structure, and future market growth. The report intends to provide innovative market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Pediatric Clinical Trials Market.

 

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