Press Release

Global Viral Vector and Plasmid DNA Manufacturing Market to grow with a CAGR of 15.30%

Increasing healthcare infrastructure and a supportive regulatory environment are the major drivers for the Global Viral Vector and Plasmid DNA Manufacturing Market.

According to TechSci Research report, “Global Viral Vector and Plasmid DNA Manufacturing Market Industry Size, Share, Trends, Competition, Opportunity and Forecast, 2018-2028”, Global Viral Vector and Plasmid DNA Manufacturing Market has valued at USD 5.49 billion in 2022 and is anticipated to witness an impressive growth in the forecast period with a CAGR of 10.89% through 2028. This can be due to collaborations and partnerships among leading companies with a diverse approach to merge the expertise of individual companies and to strengthen their position in the market.

The rapid growth in oncology applications is a significant driver for the global viral vector and plasmid DNA manufacturing market. Oncology, the study, and treatment of cancer has witnessed remarkable advancements in recent years, and gene therapy using viral vectors and plasmid DNA plays a crucial role in this field. Gene therapy has emerged as a promising approach for treating various types of cancer. Viral vectors and plasmid DNA are crucial tools for delivering therapeutic genes or RNA molecules that can target and destroy cancer cells. This has led to increased demand for these vectors in the development of gene-based cancer therapies. Cancer immunotherapies, such as chimeric antigen receptor (CAR) T-cell therapy and immune checkpoint inhibitors, have revolutionized cancer treatment. Viral vectors are used to engineer a patient’s own immune cells to recognize and attack cancer cells. Plasmid DNA is also used in the development of cancer vaccines that stimulate the immune system to target cancer-specific antigens.

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The COVID-19 outbreak is anticipated to have a favorable effect on the industry for producing viral vectors and plasmid DNA. Viral vector vaccines are another type of COVID-19 vaccine candidate that is now undergoing clinical studies. These vaccinations are probably among the COVID-19 vaccines that have been given the go-ahead for usage everywhere. Many of them have also been approved or are close to being approved.

In July 2021, to address the rapidly expanding need for plasmid DNA-based medicines and essential mRNA-based vaccinations, Thermo Fisher Scientific Inc., the industry leader in providing science services, launched a new cGMP plasmid DNA production facility in Carlsbad, California. Plasmid DNA is being utilized more frequently in gene treatments and some vaccines as a therapeutic component. Because of its benefits, such as weak immunogenicity, greater safety, and ease of fabrication, demand for materials and manufacturing capacity has skyrocketed worldwide.

Safety concerns are a significant challenge in the global viral vector and plasmid DNA manufacturing market, especially given the critical role these materials play in gene therapy and biotechnology applications. Ensuring the safety of viral vectors and plasmid DNA products is paramount. Contamination, impurities, or other quality control issues during manufacturing can pose risks to patient safety. Viral vectors, including modified viruses, must be carefully engineered to eliminate their ability to replicate or cause disease in humans. Safety concerns arise if there is a risk of viral vectors reverting to a pathogenic state or causing unintended side effects. Both viral vectors and plasmid DNA can trigger immune responses in the body. Immune reactions to these materials can reduce the efficacy of gene therapies or cause adverse effects. Gene therapies may have off-target effects, where therapeutic genes are unintentionally inserted into the wrong locations in the genome. This can lead to unintended consequences and safety concerns.

Global Viral Vector and Plasmid DNA Manufacturing Market segmentation is based on product type, application, and Region.

Based on product type, Global Viral Vector and Plasmid DNA Manufacturing Market is segmented into Plasmid DNA, Viral Vector, and Non-viral Vector. A non-viral vector, of gene therapy and biotechnology, is a delivery system that is used to introduce foreign genetic material, such as therapeutic genes or nucleic acids, into target cells without relying on the use of viruses. Unlike viral vectors, which utilize modified viruses for gene delivery, non-viral vectors do not involve the use of infectious viral particles. Non-viral vectors are considered safer and have certain advantages, although they may be less efficient in some cases. Non-viral vectors are generally considered safer because they do not involve the use of live viruses, which can potentially trigger an immune response or cause adverse effects. Non-viral vectors do not integrate genetic material into the host genome, reducing the risk of unintended genetic mutations or insertional mutagenesis.

Based on Region, North America dominated the Global Viral Vector and Plasmid DNA Manufacturing Market. The region benefits from a highly skilled and specialized workforce with expertise in bioprocessing, biomanufacturing, and gene therapy research. This pool of talent is essential for scaling up production and maintaining quality standards. North America has a large and growing demand for gene therapy products due to its sizable patient population, high healthcare expenditures, and a strong focus on addressing unmet medical needs. Many international companies and organizations collaborate with North American counterparts for research, clinical trials, and manufacturing. This fosters a global network that reinforces the region's dominance. North American companies have secured numerous patents related to gene therapy technologies, viral vectors, and plasmid DNA, giving them a competitive advantage in the global market.

Asia-pacific region to fastest growth in the Global Viral Vector and Plasmid DNA Manufacturing Market. Many countries in the Asia-Pacific region have been increasing their investments in biotechnology and life sciences. Governments and private investors have recognized the potential of gene therapy, vaccine development, and other biotechnology applications, leading to significant funding for research and development. APAC countries, including China, South Korea, India, and Japan, have witnessed substantial growth in their pharmaceutical and biotechnology industries. These industries play a pivotal role in driving the demand for viral vectors and plasmid DNA for gene therapy and biomanufacturing applications. The region has a growing pool of skilled scientists, researchers, and biopharmaceutical professionals who are contributing to the development and manufacturing of viral vectors and plasmid DNA.

Some of the major companies operating in the Global Viral Vector and Plasmid DNA Manufacturing Market include:

  • Oxford Biomedica PLC
  • Cognate BioServices Inc.
  • Cell and Gene Therapy Catapult Ltd.
  • FinVector Vision Therapies
  • Fujifilm Holdings Corporation (Fujifilm Diosynth Biotechnologies)
  • SIRION Biotech GmbH
  • Merck KGaA Inc.
  • Thermo Fisher Scientific
  • Uniqure NV
  • Catalent Inc.

 

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“Certain areas, particularly in North America, are projected to exert significant demand of gene therapies. The growth in the competitive landscape and the presence of well-established companies in the market, committed to enhance the overall wellbeing of people each year, are expected to contribute to a remarkable growth of the Global Viral Vector and Plasmid DNA Manufacturing Market in the forecast period," said Mr. Karan Chechi, Research Director with TechSci Research, a research-based Global management consulting firm.

Viral Vector and Plasmid DNA Manufacturing Market – Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028  Segmented by Product Type (Plasmid DNA, Viral Vector, and Non-viral Vector), Application (Cancer, Genetic Disorder, Infectious Disease, and Other Applications), By Region, and Competition evaluated the future growth potential of Global Viral Vector and Plasmid DNA Manufacturing Market and provides statistics & information on market size, structure, and future market growth. The report intends to provide innovative market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Viral Vector and Plasmid DNA Manufacturing Market.

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