Press Release

Optogenetics Market to grow with a CAGR of 4.01% During Forecast Period

Increasing healthcare infrastructure and a supportive regulatory environment are the major drivers for the Global Optogenetics Market.


According to TechSci Research report, “Global Optogenetics Market Industry Size, Share, Trends, Competition, Opportunity and Forecast, 2018-2028”, Global Optogenetics Market has valued at USD 545.60 million in 2022 and is anticipated to witness an impressive growth in the forecast period with a CAGR of 4.01% through 2028. This can be due to collaborations and partnerships among leading companies with a diverse approach to merge the expertise of individual companies and to strengthen their position in the market.


The increasing adoption of optogenetics in drug discovery is driving the demand for optogenetics technologies and tools in the global market. Optogenetics allows researchers to precisely control the activity of specific cells or neuronal circuits with light. This level of precision enables the investigation of cellular responses and signaling pathways with high accuracy. Understanding neural circuits and their roles in various physiological processes and diseases is critical for drug discovery. Optogenetics helps researchers map and manipulate neural circuits to identify potential drug targets. Optogenetics can be used to validate potential drug targets by selectively activating or inhibiting specific neurons or cell types. This validation step is crucial for the development of effective therapeutics. In drug discovery, functional screening of compounds or potential drug candidates is essential. Optogenetics provides a means to screen compounds for their effects on neural activity, making it a valuable tool in drug testing. Optogenetics can be applied in live animal models to assess the effects of potential drugs on behavior, neural activity, and disease progression.


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A scientific approach called optogenetics combines genetics and optical technologies. The primary purpose of it is to oversee and regulate the biological functions of neurons and other light-sensitive cells. This information aids in the understanding of individual behavior and physiology, including locomotion, learning, memory, navigation, metabolism, respiration, and sensor processing. By shedding light on the neural mechanisms behind several illnesses, including drug addiction, obsessive compulsion disorder (OCD), Parkinson's disease, stroke, chronic pain, epilepsy, social dysfunction, anxiety, and depression, optogenetics helps to advance therapeutic knowledge.


In June 2022, The NeuraLight 3D Ultra module was launched by Bruker Corporation to facilitate cutting-edge neuroscience and optogenetics research applications on Bruker's Ultima multiphoton microscopes. NeuraLight 3D Ultra offers cutting-edge 3D holographic photostimulation that is tailored for in-depth functional research on neural networks and brain computation. The NeuraLight 3D Ultra module uses a new, larger liquid crystal device that opens access to a broader field of vision, increased aiming precision, and a market-leading speed of 600 hologram frames per second, building on Bruker's unique spatial light modulator (SLM) technology. Researchers may examine the mechanisms behind behaviour, perception, and disease at a greater scale and over a longer period when combined with the imaging capabilities of the Ultima 2Pplus microscope.


Delivery and targeting are significant challenges faced by the global optogenetics market. Precise and effective delivery of optogenetic tools to target cells or tissues is crucial for successful experiments and potential therapeutic applications. Achieving specificity in targeting is essential to limit the effects of optogenetic manipulation to the desired cells or neural circuits. Non-specific targeting can lead to unintended consequences and complicate data interpretation. In the brain, for example, neural circuits can be highly complex, with different cell types intermingled. Researchers often need to target specific cell types or even individual neurons within these circuits. Achieving this level of specificity can be challenging. Targeting deep brain regions can be technically demanding. Light penetration into deep brain structures may be limited, requiring advanced optical strategies such as implantable optical fibres or gradient-index lenses.


Global Optogenetics Market segmentation is based on Light Equipment, Actuator, Sensor, Application, and Region.

Based on Actuator, Global Optogenetics Market is segmented into Channelrhodopsin, Halorhodopsin, and Archaerhodopsin. Archaerhodopsin (Arch) is a light-sensitive protein used in the field of optogenetics to inhibit or suppress the activity of neurons or other target cells. It is derived from microbial sources, specifically from archaea, which are single-celled microorganisms that thrive in extreme environments. Arch is a member of the microbial rhodopsin family of proteins, which includes other optogenetic tools like Channelrhodopsin (ChR2) and Halorhodopsin (eNpHR). Archaerhodopsin has been widely used in neuroscience research to study neural circuits, behaviors, and the role of specific neurons in various physiological processes. It has also been applied in optogenetic studies of neurological disorders and psychiatric conditions, where inhibiting or modulating neuronal activity is of therapeutic interest.


Based on Region, North America dominated the Global Optogenetics Market. North America, particularly the United States, is home to some of the world's leading research and academic institutions. These institutions have played a pivotal role in advancing optogenetics research and its applications. Researchers in North America have been at the forefront of developing and adopting optogenetic techniques. The United States and Canada have made substantial investments in the life sciences, including neuroscience and biotechnology. Government funding agencies, private foundations, and industry players have provided financial support for research projects that involve optogenetics. This funding has fueled research and innovation in the field. The region has been actively exploring the clinical applications of optogenetics, particularly in areas such as neurology, psychiatry, and ophthalmology. Clinical trials and research studies involving optogenetics as a potential therapy have been conducted in North America.


Asia-pacific region to fastest growth in the Global Optogenetics Market. The APAC region, including countries like China, Japan, South Korea, and India, has witnessed a substantial increase in research activity in the fields of neuroscience, biotechnology, and molecular biology. As optogenetics is a valuable tool for these research areas, the demand for optogenetic technologies and tools has grown. Many APAC countries have increased investment in life sciences research and biotechnology. Government funding and private investments have supported research in areas such as neuroscience, neurology, and brain-related disorders, creating fertile ground for optogenetics research. The APAC region is home to numerous academic and research institutions that focus on neuroscience and related disciplines. These institutions have been adopting optogenetic techniques for their research projects.


Some of the major companies operating in the Global Optogenetics Market include:

  • Hubner Group (Cobolt Inc.)
  • Coherent Inc.
  • Gensight Biologics S.A.
  • Laserglow Technologies
  • Noldus Information Technology Inc.
  • Judges’ Scientific PLC (Scientifica)
  • Shanghai Laser & Optics Century Co. Ltd
  • Bruker Corporation
  • Thorlabs Inc.


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“Certain areas, particularly in North America, are projected to exert significant demand for Optogenetics. The growth in the competitive landscape and the presence of well-established companies in the market, committed to enhance the overall wellbeing of people each year, are expected to contribute to a remarkable growth of the Global Optogenetics Market in the forecast period," said Mr. Karan Chechi, Research Director with TechSci Research, a research-based Global management consulting firm.


Optogenetics Market - Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented by Light Equipment (Laser and Light-emitting Diode),By  Actuator (Channelrhodopsin, Halorhodopsin, and Archaerhodopsin), By Sensor (Calcium (Aequorin, Cameleon, and Other Calcium Sensors), Chloride (Clomeleon), Membrane-gated (Mermaid), and Other Sensors), By Application (Neuroscience, Behavioral Tracking, Retinal, Disease Treatment, and Other Applications), and By Region, Competition evaluated the future growth potential of Global Optogenetics  Market and provides statistics & information on market size, structure, and future market growth. The report intends to provide innovative market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Optogenetics Market.


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