Organ-on-Chip Market to Grow with a CAGR of 25.61% through 2028
Increasing demand for electronic chip miniaturization
and accelerating healthcare expenditure in developed countries is expected to
drive the Global Organ-on-Chip Market growth in the forecast period, 2024-2028.
According to TechSci Research report, “Organ-on-Chip
Market – Global Industry Size, Share, Trends, Competition Forecast &
Opportunities, 2028”, the Global Organ-on-Chip Market stood at USD 388.20 million in 2022 and is
anticipated to grow with a CAGR of 25.61% in the forecast period, 2024-2028. The
organ-on-chip market is experiencing significant growth due to several key
factors. These include a notable increase in research funding dedicated to the
development of this technology, growing partnerships and collaborations between
pharmaceutical companies and product manufacturers, and a rising demand for
early drug detection.
Organs-on-chips technology offers numerous advantages,
such as its cost-effective production, ability to test a wide range of drug
concentrations, and its three-dimensional nature compared to traditional petri
dishes. These factors contribute to its expanding application across various
fields, further driving the development of market revenue.
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Organs-on-chips technology offers several advantages,
such as cost-effective production, the ability to test a wide range of drug
concentrations, and the three-dimensional aspect compared to traditional petri
dishes. These attributes have led to its increased application in various
fields, driving market revenue growth. Additionally, by replicating the
micro-environment of human cells, including temperature, oxygen levels, and pH,
organ-on-chip technology maintains a realistic physiological setting. The use
of microfluidics makes these devices a unique research solution, as they are
portable, user-friendly, and can be mass-produced, further contributing to
market demand and revenue growth.
Several factors contribute to the market's revenue
growth, including the growing emphasis on developing alternatives to animal
testing, increased research funding for organ-on-chip technology, and
collaborations between organ-on-chip producers and pharmaceutical companies.
The expanding applications of organ-on-chip devices in the healthcare sector,
particularly in drug screening, and the rising demand for lung- and
kidney-based organ culture are expected to drive market revenue growth in the
future. However, the market faces challenges such as the increasing costs
associated with organ-on-chip devices, limitations of certain materials used in
production, and the need for improved substrate materials.
Microchips are gaining prominence due to technological
advancements in medical equipment, enabling miniaturization and reducing
material requirements. Microfluidic chips play a crucial role in
organ-on-a-chip systems, facilitating the growth of miniature tissues that
closely resemble natural tissues. The concept behind organ-on-chip technology
is to create a micron-sized in vitro environment that mimics the behavior and
composition of an actual organ.
The aging population and the rise in chronic diseases
are expected to drive the demand for organ-on-chip technology. Additionally,
increasing healthcare costs worldwide contribute to market growth. According to
a World Health Organization (WHO) report, healthcare spending is rapidly
increasing, especially in low- and middle-income countries. The rising
prevalence of cardiovascular diseases has also led to increased demand for
organ-on-chip devices, which accurately simulate the human cardiovascular system
and offer valuable insights for personalized cardiovascular medication and
improved patient care. Ongoing research, drug application, and efficacy testing
will be key drivers for the organ-on-chip market in the forecast period.
Organ-on-chip technology has the potential to provide
early evaluation of human-specific data on drug efficacy and toxicity, offering
significant possibilities for faster and easier detection. The technology is
evolving rapidly as market participants explore newer models. With the ability
to grow human cells in micro-controlled environments, organ-on-chip devices can
simulate multiple organs on a single chip, providing detailed insights into the
functioning of the human body. These factors are expected to drive the growth
of the organ-on-chip market in the coming years.
The Global Organ-on-Chip Market is segmented into type,
offering, material type, application, end user, regional distribution, and
company.
Based on type, the lung-related application is
expected to demonstrate substantial growth throughout the forecast period. The
lung-on-chip technology, a sophisticated three-dimensional model of a
functioning human lung on a microchip, consists of human lung and blood vessel
cells. It has the ability to anticipate the absorption of airborne
nanoparticles and replicate the inflammatory response caused by microbial
pathogens. Additionally, it can evaluate the impact of environmental toxins,
assess the absorption of aerosolized therapeutics, and assess the safety and
efficacy of novel drugs. By integrating microfabrication techniques with
contemporary tissue engineering, the lung-on-chip approach presents a novel
in-vitro method for drug screening, closely mimicking the complex mechanical
and biochemical behavior of the human lung.
Furthermore, the development of innovative solutions
to address pulmonary diseases assumes paramount importance, given their high
prevalence worldwide. According to the World Health Organization's Global
Tuberculosis Report 2022, an estimated 10.6 million individuals contracted
tuberculosis (TB) globally in 2021, equivalent to 134 cases per 100,000
population. The incidence rate of TB is projected to have increased by 3.6%
between 2020 and 2021. Consequently, the escalating incidence of pulmonary
diseases, such as tuberculosis, fuels the demand for organ-on-chip technology
in disease management, thereby driving market growth during the study period. Therefore,
despite its proven efficacy, the lung-on-chip technology may benefit from
further engineering, potentially involving muscle cells, to facilitate the
evaluation of treatment effects on the lungs. This could potentially contribute
to further expansion of the market.
Based on region, North America segment is expected to
grow during the forecast period. North America is projected to demonstrate the
largest market share throughout the forecast period. The United States holds
the highest market share in the North American region, primarily due to
increased investment in research and development for drug discovery and
biotechnology. It asserts dominance in the organ-on-chip market, attributed to
factors such as a wide range of services offered by major players, including customized
chip design with specific organ arrangements, as well as increased
toxicological testing of chemicals on various types of organ cells. Significant
investments from public and private institutions are being made to support
research endeavors.
For instance, according to the National Institutes of
Health (NIH), estimated research funding for biotechnology in the United States
is projected to reach USD 7,847 million in 2021 and USD 8,142 million in 2022.
This gradual increase in research funding for biotechnology contributes to the
advancement of organ-on-chip research and drives market growth over the
forecast period. Additionally, several initiatives in North America, such as
the provision of organ-on-chip services, approvals, and product launches,
contribute to market expansion. For example, in May 2022, Nikon Instruments
Inc. announced the initiation of organ-on-a-chip imaging and analysis contract
services in the United States, specifically targeted towards research and
development for drug discovery. Similarly, in March 2021, AIM Biotech
introduced a contract research service utilizing their organ-on-a-chip
technology to expedite and enhance drug discovery and development. These
services further broaden the scope of organ-on-a-chip imaging, thus fostering
market growth. Therefore, the aforementioned factors are expected to
significantly impact the growth of this market segment.
Major companies operating in
Global Organ-on-Chip Market are:
- Altis Biosystems
- AxoSim Inc.
- BiomimX SRL
- Emulate Inc.
- Hesperos
- Allevi Inc.
- InSphero AG
- MIMETAS BV
- Nortis Inc.
- Hesperos, Inc.
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“There is currently a rise in the demand for
organ-on-chips in drug screening, driven by several key factors. Firstly, the
use of organ-on-chips helps reduce employee healthcare costs, improve morale,
productivity, and performance, and decrease absenteeism, accidents, downtime,
turnover, and theft. Additionally, there is a growing demand for lung and
kidney-based organ culture devices. Moreover, the availability of
laboratory-engineered functional organs worldwide is increasing. This, coupled
with the escalating demand for alternatives to animal testing through research
activities on organ-on-chip devices for new drug development, is propelling
market growth. Furthermore, advancements in cell biology, microfabrication, and
microfluidics have led to the rising adoption of organ-on-chips technology,
offering lucrative growth opportunities for industry investors. The healthcare
industry also benefits from the application of organ-on-chips devices, enabling
real-time imaging and in vitro analysis of biochemical, genetic, and metabolic
activities of living cells in functional tissues. Lastly, key market players
are heavily investing in research and development (R&D) activities to
develop new solutions for treating pulmonary diseases, further catalyzing the
demand for organ-on-chips technology.,” said Mr. Karan Chechi, Research
Director with TechSci Research, a research-based management consulting firm.
“Organ-on-Chip Market Segmented
By Type (Liver, Heart, Lung, Kidney, Others), By Offering (Products v/s
Services), By Material Type (Polymer, PDMS, Glass, Silicon, Others), By Application
(Physiological Model Development, Drug Discovery, Toxicological Research,
Molecular Biology, Others), By End User (Pharmaceutical & Biotechnology
Companies, Academic & Research Institutes, Others), By Region and Competition, Forecast &
Opportunities, 2018-2028F”, has evaluated the future growth potential of Global
Organ-on-Chip Market and provides statistics & information on market size,
structure and future market growth. The report intends to provide cutting-edge
market intelligence and help decision makers take sound investment decisions.
Besides, the report also identifies and analyzes the emerging trends along with
essential drivers, challenges, and opportunities in Global Organ-on-Chip
Market.
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